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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FTO
All Species:
33.64
Human Site:
Y108
Identified Species:
92.5
UniProt:
Q9C0B1
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9C0B1
NP_001073901.1
505
58282
Y108
N
P
G
C
T
Y
K
Y
L
N
T
R
L
F
T
Chimpanzee
Pan troglodytes
XP_510968
505
58196
Y108
N
P
G
C
T
Y
K
Y
L
N
T
R
L
F
T
Rhesus Macaque
Macaca mulatta
XP_001092038
515
58499
Y118
N
P
G
C
T
Y
K
Y
L
N
T
R
L
F
T
Dog
Lupus familis
XP_535301
571
65505
Y175
N
P
G
C
T
Y
K
Y
L
N
T
R
L
F
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGW1
502
57988
Y108
D
P
G
C
T
Y
K
Y
L
N
T
R
L
F
T
Rat
Rattus norvegicus
Q2A121
502
57953
Y108
D
P
G
C
T
Y
K
Y
L
N
T
R
L
F
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520255
734
82842
Y324
Q
P
G
H
T
Y
R
Y
L
E
T
R
L
F
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Q68F54
501
58509
Y108
R
P
G
Y
T
Y
K
Y
L
N
T
R
L
F
A
Zebra Danio
Brachydanio rerio
XP_001345910
681
78440
Y119
Q
P
G
Y
T
Y
R
Y
L
D
T
R
L
F
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
89.9
80.7
N.A.
86.7
87.1
N.A.
41.9
N.A.
53
38.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
92.2
83.7
N.A.
92.4
92.2
N.A.
51
N.A.
66.9
51.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
66.6
N.A.
80
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
73.3
N.A.
80
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
23
% A
% Cys:
0
0
0
67
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
23
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% F
% Gly:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
78
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
100
0
0
0
100
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
45
0
0
0
0
0
0
0
0
78
0
0
0
0
0
% N
% Pro:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
23
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
12
0
0
0
0
0
23
0
0
0
0
100
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
100
0
0
0
0
0
100
0
0
0
78
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
23
0
100
0
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _