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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEMA4C
All Species:
24.55
Human Site:
S742
Identified Species:
49.09
UniProt:
Q9C0C4
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9C0C4
NP_060259.4
833
92623
S742
G
Y
Y
Y
S
D
G
S
L
K
I
V
P
G
H
Chimpanzee
Pan troglodytes
XP_515634
858
95093
S767
G
Y
Y
Y
S
D
G
S
L
K
I
V
P
G
H
Rhesus Macaque
Macaca mulatta
XP_001100467
833
92394
S742
G
Y
Y
Y
S
D
G
S
L
K
I
V
P
G
H
Dog
Lupus familis
XP_538464
849
94187
S758
G
Y
Y
Y
S
D
G
S
L
K
I
V
P
G
H
Cat
Felis silvestris
Mouse
Mus musculus
Q64151
834
92538
S743
G
Y
Y
Y
S
D
G
S
L
K
I
V
P
G
H
Rat
Rattus norvegicus
Q9Z143
776
84280
G709
D
K
V
G
L
D
L
G
A
P
P
S
G
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520007
465
51429
N400
I
D
A
W
H
R
R
N
G
Y
A
S
S
L
E
Chicken
Gallus gallus
Q90663
761
87282
L694
E
G
R
V
R
D
L
L
T
E
S
R
L
R
Y
Frog
Xenopus laevis
NP_001131042
834
93072
S738
S
F
Y
Y
S
D
G
S
L
K
I
V
P
G
H
Zebra Danio
Brachydanio rerio
Q9YHX4
766
85599
V698
L
P
C
L
H
R
R
V
K
A
T
Q
N
R
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24322
850
95478
S746
D
N
F
G
T
L
R
S
H
Q
V
M
G
D
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17330
712
78063
H647
T
T
A
T
K
V
D
H
G
F
V
P
Q
S
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.7
97.2
91.1
N.A.
87.7
34.2
N.A.
40.7
31.5
59.7
34.9
N.A.
27.8
N.A.
26.8
N.A.
Protein Similarity:
100
93.5
98.5
94.2
N.A.
92.9
49.9
N.A.
45.3
46.5
73.9
50.4
N.A.
44.5
N.A.
44.2
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
0
6.6
86.6
6.6
N.A.
6.6
N.A.
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
6.6
N.A.
13.3
20
93.3
6.6
N.A.
46.6
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
0
0
0
0
0
9
9
9
0
0
0
0
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
9
0
0
0
67
9
0
0
0
0
0
0
9
0
% D
% Glu:
9
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% E
% Phe:
0
9
9
0
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
42
9
0
17
0
0
50
9
17
0
0
0
17
50
0
% G
% His:
0
0
0
0
17
0
0
9
9
0
0
0
0
0
59
% H
% Ile:
9
0
0
0
0
0
0
0
0
0
50
0
0
0
0
% I
% Lys:
0
9
0
0
9
0
0
0
9
50
0
0
0
0
9
% K
% Leu:
9
0
0
9
9
9
17
9
50
0
0
0
9
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
9
0
0
0
0
9
0
9
% N
% Pro:
0
9
0
0
0
0
0
0
0
9
9
9
50
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
9
0
9
9
0
0
% Q
% Arg:
0
0
9
0
9
17
25
0
0
0
0
9
0
17
0
% R
% Ser:
9
0
0
0
50
0
0
59
0
0
9
17
9
9
0
% S
% Thr:
9
9
0
9
9
0
0
0
9
0
9
0
0
9
9
% T
% Val:
0
0
9
9
0
9
0
9
0
0
17
50
0
0
0
% V
% Trp:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
42
50
50
0
0
0
0
0
9
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _