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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEMA4C All Species: 18.79
Human Site: Y736 Identified Species: 37.58
UniProt: Q9C0C4 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9C0C4 NP_060259.4 833 92623 Y736 K L W D P V G Y Y Y S D G S L
Chimpanzee Pan troglodytes XP_515634 858 95093 Y761 K L W D P V G Y Y Y S D G S L
Rhesus Macaque Macaca mulatta XP_001100467 833 92394 Y736 K L W D P V G Y Y Y S D G S L
Dog Lupus familis XP_538464 849 94187 Y752 K L W D P V G Y Y Y S D G S L
Cat Felis silvestris
Mouse Mus musculus Q64151 834 92538 Y737 K L W D P V G Y Y Y S D G S L
Rat Rattus norvegicus Q9Z143 776 84280 K703 R E L L A R D K V G L D L G A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520007 465 51429 D394 P R P G S C I D A W H R R N G
Chicken Gallus gallus Q90663 761 87282 G688 Q K T E D E E G R V R D L L T
Frog Xenopus laevis NP_001131042 834 93072 F732 K L W D P S S F Y Y S D G S L
Zebra Danio Brachydanio rerio Q9YHX4 766 85599 P692 Y K G H L S L P C L H R R V K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24322 850 95478 N740 Q S Y R G R D N F G T L R S H
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q17330 712 78063 T641 T R H D S L T T A T K V D H G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.7 97.2 91.1 N.A. 87.7 34.2 N.A. 40.7 31.5 59.7 34.9 N.A. 27.8 N.A. 26.8 N.A.
Protein Similarity: 100 93.5 98.5 94.2 N.A. 92.9 49.9 N.A. 45.3 46.5 73.9 50.4 N.A. 44.5 N.A. 44.2 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 6.6 N.A. 0 6.6 80 0 N.A. 6.6 N.A. 6.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 13.3 N.A. 13.3 20 86.6 0 N.A. 33.3 N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 9 0 0 0 17 0 0 0 0 0 9 % A
% Cys: 0 0 0 0 0 9 0 0 9 0 0 0 0 0 0 % C
% Asp: 0 0 0 59 9 0 17 9 0 0 0 67 9 0 0 % D
% Glu: 0 9 0 9 0 9 9 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 9 9 0 0 0 0 0 0 % F
% Gly: 0 0 9 9 9 0 42 9 0 17 0 0 50 9 17 % G
% His: 0 0 9 9 0 0 0 0 0 0 17 0 0 9 9 % H
% Ile: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % I
% Lys: 50 17 0 0 0 0 0 9 0 0 9 0 0 0 9 % K
% Leu: 0 50 9 9 9 9 9 0 0 9 9 9 17 9 50 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 9 0 0 0 0 0 9 0 % N
% Pro: 9 0 9 0 50 0 0 9 0 0 0 0 0 0 0 % P
% Gln: 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 9 17 0 9 0 17 0 0 9 0 9 17 25 0 0 % R
% Ser: 0 9 0 0 17 17 9 0 0 0 50 0 0 59 0 % S
% Thr: 9 0 9 0 0 0 9 9 0 9 9 0 0 0 9 % T
% Val: 0 0 0 0 0 42 0 0 9 9 0 9 0 9 0 % V
% Trp: 0 0 50 0 0 0 0 0 0 9 0 0 0 0 0 % W
% Tyr: 9 0 9 0 0 0 0 42 50 50 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _