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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AMBRA1 All Species: 16.97
Human Site: S430 Identified Species: 46.67
UniProt: Q9C0C7 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9C0C7 NP_060219.2 1298 142507 S430 V L S L N S R S E A E S M P P
Chimpanzee Pan troglodytes XP_001163113 1208 132805 S356 R T S A S S V S L L S V L R Q
Rhesus Macaque Macaca mulatta XP_001112256 1298 142465 S430 V L S L N S R S E A E S M P P
Dog Lupus familis XP_540754 1211 132916 S359 A S S V S L L S V L R Q Q E G
Cat Felis silvestris
Mouse Mus musculus A2AH22 1300 142860 S431 V L T L N S R S E V E S M P P
Rat Rattus norvegicus NP_001127813 1300 142989 S431 V L T L N S R S E V E S M P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001233289 1300 142720 T430 G G S D W S R T V L N M S S R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001342016 1003 110813 L151 F H P T A Q L L L I A T N N E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797133 781 86047
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.9 99 89.8 N.A. 95.6 95.9 N.A. N.A. 83 N.A. 47.6 N.A. N.A. N.A. N.A. 27.6
Protein Similarity: 100 93 99.3 90.7 N.A. 97.1 97.3 N.A. N.A. 88.9 N.A. 58.7 N.A. N.A. N.A. N.A. 37.6
P-Site Identity: 100 20 100 13.3 N.A. 86.6 86.6 N.A. N.A. 20 N.A. 0 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 33.3 100 26.6 N.A. 93.3 93.3 N.A. N.A. 26.6 N.A. 6.6 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 0 12 12 0 0 0 0 23 12 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 45 0 45 0 0 12 12 % E
% Phe: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 12 12 0 0 0 0 0 0 0 0 0 0 0 0 12 % G
% His: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 45 0 45 0 12 23 12 23 34 0 0 12 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 12 45 0 0 % M
% Asn: 0 0 0 0 45 0 0 0 0 0 12 0 12 12 0 % N
% Pro: 0 0 12 0 0 0 0 0 0 0 0 0 0 45 45 % P
% Gln: 0 0 0 0 0 12 0 0 0 0 0 12 12 0 12 % Q
% Arg: 12 0 0 0 0 0 56 0 0 0 12 0 0 12 12 % R
% Ser: 0 12 56 0 23 67 0 67 0 0 12 45 12 12 0 % S
% Thr: 0 12 23 12 0 0 0 12 0 0 0 12 0 0 0 % T
% Val: 45 0 0 12 0 0 12 0 23 23 0 12 0 0 0 % V
% Trp: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _