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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE2O All Species: 16.97
Human Site: S1166 Identified Species: 31.11
UniProt: Q9C0C9 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9C0C9 NP_071349.3 1292 141293 S1166 P N G V P K A S S S P E P P A
Chimpanzee Pan troglodytes XP_001139963 1392 151306 Y1240 D I Q L P N I Y P A V P P H F
Rhesus Macaque Macaca mulatta XP_001099166 1374 150150 S1248 P N G V P K A S S S P E P P A
Dog Lupus familis XP_540449 1328 145864 S1202 P N G I P K D S S S P E P P A
Cat Felis silvestris
Mouse Mus musculus Q6ZPJ3 1288 140799 S1163 P N G A P K D S S S L E P M A
Rat Rattus norvegicus XP_221132 1291 140971 S1166 P N G V P K D S S S L E P Q A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507962 1095 118343 L971 L F L F D I Q L P N I Y P A V
Chicken Gallus gallus XP_415619 1288 141077 A1157 A D P L S G S A E Q G A A A E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_692656 586 64314 R462 H F A C S G W R L V H R L E S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651170 1398 156627 L1233 S S T M L Q V L V S I Q G L I
Honey Bee Apis mellifera XP_001120701 1287 145895 P1158 H P L S P V T P T T F K Q I S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002313703 1079 118536 N955 L N S K P Y F N E A G Y D K Q
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZVX1 1102 122164 E978 N S K P Y F N E A G Y D K Q V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 82.4 93.3 90.9 N.A. 94.1 94.2 N.A. 69.1 77.6 N.A. 28 N.A. 21.8 20.7 N.A. N.A.
Protein Similarity: 100 82.9 93.6 92.9 N.A. 96.1 96 N.A. 74.3 83.9 N.A. 35.2 N.A. 39.9 35.6 N.A. N.A.
P-Site Identity: 100 13.3 100 86.6 N.A. 73.3 80 N.A. 6.6 0 N.A. 0 N.A. 6.6 6.6 N.A. N.A.
P-Site Similarity: 100 26.6 100 93.3 N.A. 73.3 80 N.A. 13.3 26.6 N.A. 6.6 N.A. 33.3 33.3 N.A. N.A.
Percent
Protein Identity: 25.7 N.A. N.A. 23.3 N.A. N.A.
Protein Similarity: 41.8 N.A. N.A. 39.9 N.A. N.A.
P-Site Identity: 13.3 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 26.6 N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 8 0 0 16 8 8 16 0 8 8 16 39 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 0 0 8 0 24 0 0 0 0 8 8 0 0 % D
% Glu: 0 0 0 0 0 0 0 8 16 0 0 39 0 8 8 % E
% Phe: 0 16 0 8 0 8 8 0 0 0 8 0 0 0 8 % F
% Gly: 0 0 39 0 0 16 0 0 0 8 16 0 8 0 0 % G
% His: 16 0 0 0 0 0 0 0 0 0 8 0 0 8 0 % H
% Ile: 0 8 0 8 0 8 8 0 0 0 16 0 0 8 8 % I
% Lys: 0 0 8 8 0 39 0 0 0 0 0 8 8 8 0 % K
% Leu: 16 0 16 16 8 0 0 16 8 0 16 0 8 8 0 % L
% Met: 0 0 0 8 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 8 47 0 0 0 8 8 8 0 8 0 0 0 0 0 % N
% Pro: 39 8 8 8 62 0 0 8 16 0 24 8 54 24 0 % P
% Gln: 0 0 8 0 0 8 8 0 0 8 0 8 8 16 8 % Q
% Arg: 0 0 0 0 0 0 0 8 0 0 0 8 0 0 0 % R
% Ser: 8 16 8 8 16 0 8 39 39 47 0 0 0 0 16 % S
% Thr: 0 0 8 0 0 0 8 0 8 8 0 0 0 0 0 % T
% Val: 0 0 0 24 0 8 8 0 8 8 8 0 0 0 16 % V
% Trp: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 8 0 8 0 0 8 16 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _