KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE2O
All Species:
22.42
Human Site:
S627
Identified Species:
41.11
UniProt:
Q9C0C9
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9C0C9
NP_071349.3
1292
141293
S627
K
W
F
K
L
R
P
S
G
D
D
V
E
L
I
Chimpanzee
Pan troglodytes
XP_001139963
1392
151306
I623
L
K
K
Q
V
V
R
I
M
S
C
S
P
D
T
Rhesus Macaque
Macaca mulatta
XP_001099166
1374
150150
S708
K
W
F
K
L
R
P
S
G
D
D
V
E
L
I
Dog
Lupus familis
XP_540449
1328
145864
S662
K
W
F
K
L
R
P
S
G
D
D
V
E
L
I
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZPJ3
1288
140799
S622
K
W
F
K
L
R
P
S
G
D
D
V
E
L
I
Rat
Rattus norvegicus
XP_221132
1291
140971
S625
K
W
F
K
L
R
P
S
G
D
D
V
E
L
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507962
1095
118343
L490
T
P
L
S
I
K
N
L
K
R
K
H
K
K
K
Chicken
Gallus gallus
XP_415619
1288
141077
S628
K
W
F
K
L
K
S
S
G
D
D
V
E
L
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_692656
586
64314
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651170
1398
156627
I628
W
F
N
I
Y
T
N
I
D
N
P
I
P
L
F
Honey Bee
Apis mellifera
XP_001120701
1287
145895
I666
A
H
I
E
K
A
R
I
A
M
S
R
L
E
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002313703
1079
118536
N474
G
T
I
E
R
G
L
N
S
T
T
L
I
P
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZVX1
1102
122164
K496
S
E
Q
Y
V
V
E
K
T
S
D
D
G
D
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.4
93.3
90.9
N.A.
94.1
94.2
N.A.
69.1
77.6
N.A.
28
N.A.
21.8
20.7
N.A.
N.A.
Protein Similarity:
100
82.9
93.6
92.9
N.A.
96.1
96
N.A.
74.3
83.9
N.A.
35.2
N.A.
39.9
35.6
N.A.
N.A.
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
0
86.6
N.A.
0
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
20
93.3
N.A.
0
N.A.
26.6
6.6
N.A.
N.A.
Percent
Protein Identity:
25.7
N.A.
N.A.
23.3
N.A.
N.A.
Protein Similarity:
41.8
N.A.
N.A.
39.9
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
47
54
8
0
16
0
% D
% Glu:
0
8
0
16
0
0
8
0
0
0
0
0
47
8
8
% E
% Phe:
0
8
47
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
8
0
0
0
0
8
0
0
47
0
0
0
8
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
16
8
8
0
0
24
0
0
0
8
8
0
54
% I
% Lys:
47
8
8
47
8
16
0
8
8
0
8
0
8
8
8
% K
% Leu:
8
0
8
0
47
0
8
8
0
0
0
8
8
54
0
% L
% Met:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
16
8
0
8
0
0
0
0
8
% N
% Pro:
0
8
0
0
0
0
39
0
0
0
8
0
16
8
0
% P
% Gln:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
39
16
0
0
8
0
8
0
0
0
% R
% Ser:
8
0
0
8
0
0
8
47
8
16
8
8
0
0
0
% S
% Thr:
8
8
0
0
0
8
0
0
8
8
8
0
0
0
8
% T
% Val:
0
0
0
0
16
16
0
0
0
0
0
47
0
0
0
% V
% Trp:
8
47
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _