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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE2O All Species: 28.18
Human Site: S641 Identified Species: 51.67
UniProt: Q9C0C9 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9C0C9 NP_071349.3 1292 141293 S641 I G E E E D V S V Y D I A D H
Chimpanzee Pan troglodytes XP_001139963 1392 151306 S637 T Q C S R D H S M E D P D K K
Rhesus Macaque Macaca mulatta XP_001099166 1374 150150 S722 I G E E E D V S V Y D I A D H
Dog Lupus familis XP_540449 1328 145864 S676 I G E E E D V S V Y D I A D H
Cat Felis silvestris
Mouse Mus musculus Q6ZPJ3 1288 140799 S636 I G E E E D V S V Y D I A D H
Rat Rattus norvegicus XP_221132 1291 140971 S639 I G E E E D V S V Y D I A D H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507962 1095 118343 E504 K K T K V S R E F K P G D R V
Chicken Gallus gallus XP_415619 1288 141077 S642 I G E E E D V S V Y D I A D H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_692656 586 64314
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651170 1398 156627 S642 F K G L E E L S V Y D M K D H
Honey Bee Apis mellifera XP_001120701 1287 145895 S680 E I F T Q N P S L Q T T E V M
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002313703 1079 118536 E488 I D S P G D H E F I S E Q Y V
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZVX1 1102 122164 A510 N T T E P R R A G V V K N V N
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 82.4 93.3 90.9 N.A. 94.1 94.2 N.A. 69.1 77.6 N.A. 28 N.A. 21.8 20.7 N.A. N.A.
Protein Similarity: 100 82.9 93.6 92.9 N.A. 96.1 96 N.A. 74.3 83.9 N.A. 35.2 N.A. 39.9 35.6 N.A. N.A.
P-Site Identity: 100 20 100 100 N.A. 100 100 N.A. 0 100 N.A. 0 N.A. 46.6 6.6 N.A. N.A.
P-Site Similarity: 100 26.6 100 100 N.A. 100 100 N.A. 6.6 100 N.A. 0 N.A. 66.6 26.6 N.A. N.A.
Percent
Protein Identity: 25.7 N.A. N.A. 23.3 N.A. N.A.
Protein Similarity: 41.8 N.A. N.A. 39.9 N.A. N.A.
P-Site Identity: 13.3 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 13.3 N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 8 0 0 0 0 47 0 0 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 62 0 0 0 0 62 0 16 54 0 % D
% Glu: 8 0 47 54 54 8 0 16 0 8 0 8 8 0 0 % E
% Phe: 8 0 8 0 0 0 0 0 16 0 0 0 0 0 0 % F
% Gly: 0 47 8 0 8 0 0 0 8 0 0 8 0 0 0 % G
% His: 0 0 0 0 0 0 16 0 0 0 0 0 0 0 54 % H
% Ile: 54 8 0 0 0 0 0 0 0 8 0 47 0 0 0 % I
% Lys: 8 16 0 8 0 0 0 0 0 8 0 8 8 8 8 % K
% Leu: 0 0 0 8 0 0 8 0 8 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 8 0 0 8 0 0 8 % M
% Asn: 8 0 0 0 0 8 0 0 0 0 0 0 8 0 8 % N
% Pro: 0 0 0 8 8 0 8 0 0 0 8 8 0 0 0 % P
% Gln: 0 8 0 0 8 0 0 0 0 8 0 0 8 0 0 % Q
% Arg: 0 0 0 0 8 8 16 0 0 0 0 0 0 8 0 % R
% Ser: 0 0 8 8 0 8 0 70 0 0 8 0 0 0 0 % S
% Thr: 8 8 16 8 0 0 0 0 0 0 8 8 0 0 0 % T
% Val: 0 0 0 0 8 0 47 0 54 8 8 0 0 16 16 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 54 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _