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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE2O
All Species:
23.33
Human Site:
Y1251
Identified Species:
42.78
UniProt:
Q9C0C9
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9C0C9
NP_071349.3
1292
141293
Y1251
F
L
P
E
K
S
G
Y
P
D
I
G
F
P
L
Chimpanzee
Pan troglodytes
XP_001139963
1392
151306
V1337
E
M
A
L
I
R
V
V
Q
S
M
T
Q
L
V
Rhesus Macaque
Macaca mulatta
XP_001099166
1374
150150
Y1333
F
L
P
E
K
S
G
Y
P
D
I
G
F
P
L
Dog
Lupus familis
XP_540449
1328
145864
Y1287
F
L
P
E
K
S
G
Y
P
D
I
G
F
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZPJ3
1288
140799
Y1247
F
L
P
E
K
S
G
Y
P
D
I
G
F
P
L
Rat
Rattus norvegicus
XP_221132
1291
140971
Y1250
F
L
P
E
K
S
G
Y
P
D
I
G
F
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507962
1095
118343
S1055
Q
D
P
I
S
P
V
S
G
R
A
L
R
G
A
Chicken
Gallus gallus
XP_415619
1288
141077
Y1247
F
L
P
E
K
S
G
Y
P
D
I
G
F
P
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_692656
586
64314
C546
D
L
S
Q
N
S
E
C
D
S
S
L
V
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651170
1398
156627
C1339
P
V
E
Y
K
A
S
C
E
L
P
E
F
P
L
Honey Bee
Apis mellifera
XP_001120701
1287
145895
K1243
I
V
E
H
S
S
K
K
R
N
E
E
N
C
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002313703
1079
118536
E1039
E
A
S
V
S
S
K
E
S
S
N
L
S
S
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZVX1
1102
122164
S1062
A
S
V
I
D
E
R
S
S
A
N
S
T
S
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.4
93.3
90.9
N.A.
94.1
94.2
N.A.
69.1
77.6
N.A.
28
N.A.
21.8
20.7
N.A.
N.A.
Protein Similarity:
100
82.9
93.6
92.9
N.A.
96.1
96
N.A.
74.3
83.9
N.A.
35.2
N.A.
39.9
35.6
N.A.
N.A.
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
6.6
100
N.A.
13.3
N.A.
26.6
6.6
N.A.
N.A.
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
6.6
100
N.A.
20
N.A.
40
20
N.A.
N.A.
Percent
Protein Identity:
25.7
N.A.
N.A.
23.3
N.A.
N.A.
Protein Similarity:
41.8
N.A.
N.A.
39.9
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
0
8
0
0
0
8
8
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
16
0
0
0
0
0
8
0
% C
% Asp:
8
8
0
0
8
0
0
0
8
47
0
0
0
0
0
% D
% Glu:
16
0
16
47
0
8
8
8
8
0
8
16
0
0
0
% E
% Phe:
47
0
0
0
0
0
0
0
0
0
0
0
54
0
0
% F
% Gly:
0
0
0
0
0
0
47
0
8
0
0
47
0
16
8
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
16
8
0
0
0
0
0
47
0
0
0
0
% I
% Lys:
0
0
0
0
54
0
16
8
0
0
0
0
0
0
8
% K
% Leu:
0
54
0
8
0
0
0
0
0
8
0
24
0
8
54
% L
% Met:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
8
16
0
8
0
0
% N
% Pro:
8
0
54
0
0
8
0
0
47
0
8
0
0
54
0
% P
% Gln:
8
0
0
8
0
0
0
0
8
0
0
0
8
0
0
% Q
% Arg:
0
0
0
0
0
8
8
0
8
8
0
0
8
0
0
% R
% Ser:
0
8
16
0
24
70
8
16
16
24
8
8
8
16
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% T
% Val:
0
16
8
8
0
0
16
8
0
0
0
0
8
0
24
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
47
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _