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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZYG11B All Species: 25.76
Human Site: S159 Identified Species: 56.67
UniProt: Q9C0D3 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9C0D3 NP_078922.1 744 83921 S159 D P Y E R C F S R L S G L R A
Chimpanzee Pan troglodytes XP_001139134 796 89462 S211 D P Y E R C F S R L S G L R A
Rhesus Macaque Macaca mulatta XP_001110332 766 88145 E172 L V K D F T F E G F S R L R F
Dog Lupus familis XP_539612 818 91614 S233 D P Y E R C F S R L S G L R A
Cat Felis silvestris
Mouse Mus musculus Q3UFS0 744 83973 S159 D P Y E R C F S R L S G L R A
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_422479 735 83205 S150 D P Y E R C F S Q L S G L R A
Frog Xenopus laevis A0JMZ3 732 82944 S150 D P Y E R C F S Q L S G L R V
Zebra Danio Brachydanio rerio Q5TYQ1 746 83647 S159 E P S R R C F S A M Q G L R A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W0E8 793 90347 V172 C P H L R R L V L N G V V M H
Honey Bee Apis mellifera XP_392631 761 85731 K176 C V V V T L N K L R S L H T L
Nematode Worm Caenorhab. elegans P21541 799 90762 R155 N W P T Y V A R K L P R L E S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.4 26.5 90.3 N.A. 98.1 N.A. N.A. N.A. 93.2 83.1 70.3 N.A. 26.4 41 26.7 N.A.
Protein Similarity: 100 93.4 48 90.5 N.A. 99.3 N.A. N.A. N.A. 96.6 90.7 81.5 N.A. 46 59.6 47.8 N.A.
P-Site Identity: 100 100 26.6 100 N.A. 100 N.A. N.A. N.A. 93.3 86.6 60 N.A. 13.3 6.6 13.3 N.A.
P-Site Similarity: 100 100 33.3 100 N.A. 100 N.A. N.A. N.A. 100 93.3 73.3 N.A. 26.6 6.6 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 10 0 10 0 0 0 0 0 55 % A
% Cys: 19 0 0 0 0 64 0 0 0 0 0 0 0 0 0 % C
% Asp: 55 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 10 0 0 55 0 0 0 10 0 0 0 0 0 10 0 % E
% Phe: 0 0 0 0 10 0 73 0 0 10 0 0 0 0 10 % F
% Gly: 0 0 0 0 0 0 0 0 10 0 10 64 0 0 0 % G
% His: 0 0 10 0 0 0 0 0 0 0 0 0 10 0 10 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 10 0 0 0 0 10 10 0 0 0 0 0 0 % K
% Leu: 10 0 0 10 0 10 10 0 19 64 0 10 82 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 10 0 0 0 10 0 % M
% Asn: 10 0 0 0 0 0 10 0 0 10 0 0 0 0 0 % N
% Pro: 0 73 10 0 0 0 0 0 0 0 10 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 19 0 10 0 0 0 0 % Q
% Arg: 0 0 0 10 73 10 0 10 37 10 0 19 0 73 0 % R
% Ser: 0 0 10 0 0 0 0 64 0 0 73 0 0 0 10 % S
% Thr: 0 0 0 10 10 10 0 0 0 0 0 0 0 10 0 % T
% Val: 0 19 10 10 0 10 0 10 0 0 0 10 10 0 10 % V
% Trp: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 55 0 10 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _