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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XPO4
All Species:
40
Human Site:
S619
Identified Species:
73.33
UniProt:
Q9C0E2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9C0E2
NP_071904.4
1151
130139
S619
L
R
V
S
E
V
E
S
R
A
I
R
A
D
L
Chimpanzee
Pan troglodytes
XP_001148853
1150
129990
S618
L
R
V
S
E
V
E
S
R
A
I
R
A
D
L
Rhesus Macaque
Macaca mulatta
XP_001085699
1150
130004
S618
L
R
V
S
E
V
E
S
R
A
I
R
A
D
L
Dog
Lupus familis
XP_534538
1160
131261
S618
L
R
V
S
E
V
E
S
R
A
I
R
A
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9ESJ0
1151
129947
S619
L
R
V
S
E
V
E
S
R
A
I
R
A
D
L
Rat
Rattus norvegicus
NP_001099512
1148
129647
S616
L
R
V
S
E
V
E
S
R
A
I
R
A
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518911
1303
147532
S771
L
R
A
S
E
V
E
S
R
A
I
R
A
D
L
Chicken
Gallus gallus
Q5ZMR9
1154
130298
S622
L
R
V
S
E
V
E
S
R
A
I
R
A
N
L
Frog
Xenopus laevis
Q499Y0
1150
130077
S618
L
R
A
S
E
V
E
S
R
A
T
R
A
D
L
Zebra Danio
Brachydanio rerio
Q802D3
1150
129208
S618
L
R
T
S
E
V
E
S
R
A
T
R
A
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121681
806
92179
E327
E
K
D
L
F
S
S
E
F
F
K
Q
T
F
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786031
786
88327
V307
A
S
I
L
N
H
L
V
T
K
F
P
I
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_187099
1117
123786
S623
L
D
A
E
M
R
S
S
I
F
S
P
R
L
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
99.6
98.8
N.A.
98.5
98
N.A.
85
95.4
93.6
86.6
N.A.
N.A.
27.9
N.A.
34.4
Protein Similarity:
100
99.9
99.9
99.1
N.A.
99.3
99.3
N.A.
87.1
98.2
97.3
94
N.A.
N.A.
45.3
N.A.
49
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
93.3
86.6
80
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
100
86.6
80
N.A.
N.A.
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
24
0
0
0
0
0
0
77
0
0
77
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
0
0
0
0
0
0
0
0
0
70
0
% D
% Glu:
8
0
0
8
77
0
77
8
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
8
16
8
0
0
8
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
8
0
62
0
8
0
8
% I
% Lys:
0
8
0
0
0
0
0
0
0
8
8
0
0
0
0
% K
% Leu:
85
0
0
16
0
0
8
0
0
0
0
0
0
8
85
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
77
0
0
0
8
0
0
77
0
0
77
8
0
0
% R
% Ser:
0
8
0
77
0
8
16
85
0
0
8
0
0
8
0
% S
% Thr:
0
0
8
0
0
0
0
0
8
0
16
0
8
0
0
% T
% Val:
0
0
54
0
0
77
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _