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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: XPO4 All Species: 30.61
Human Site: S665 Identified Species: 56.11
UniProt: Q9C0E2 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9C0E2 NP_071904.4 1151 130139 S665 D Q I S L P F S T A F G A D T
Chimpanzee Pan troglodytes XP_001148853 1150 129990 S664 D Q I S L P F S T A F G A D T
Rhesus Macaque Macaca mulatta XP_001085699 1150 130004 S664 D Q I S L P F S T A F G A D T
Dog Lupus familis XP_534538 1160 131261 S664 D Q I S L P F S T A F G A D T
Cat Felis silvestris
Mouse Mus musculus Q9ESJ0 1151 129947 S665 D Q I S L P L S T A F G A D T
Rat Rattus norvegicus NP_001099512 1148 129647 S662 D Q I S L P L S T A F G A D T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518911 1303 147532 N817 D Q I S L P F N T A F G T D T
Chicken Gallus gallus Q5ZMR9 1154 130298 S668 D Q I S L P F S T A F G A D T
Frog Xenopus laevis Q499Y0 1150 130077 N664 D Q I S L P F N T A F G A D T
Zebra Danio Brachydanio rerio Q802D3 1150 129208 S664 G Q I S M P L S T A F G A D T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001121681 806 92179 R371 L A Q L I E D R I F K L R E N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786031 786 88327 D351 E E A L H Q D D Q Q Y M E A F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_187099 1117 123786 L667 S L P S R A C L F T Y F N E H
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 99.6 98.8 N.A. 98.5 98 N.A. 85 95.4 93.6 86.6 N.A. N.A. 27.9 N.A. 34.4
Protein Similarity: 100 99.9 99.9 99.1 N.A. 99.3 99.3 N.A. 87.1 98.2 97.3 94 N.A. N.A. 45.3 N.A. 49
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 86.6 100 93.3 80 N.A. N.A. 0 N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 93.3 100 100 86.6 N.A. N.A. 13.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 27.7 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 49 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 0 0 8 0 0 0 77 0 0 70 8 0 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % C
% Asp: 70 0 0 0 0 0 16 8 0 0 0 0 0 77 0 % D
% Glu: 8 8 0 0 0 8 0 0 0 0 0 0 8 16 0 % E
% Phe: 0 0 0 0 0 0 54 0 8 8 77 8 0 0 8 % F
% Gly: 8 0 0 0 0 0 0 0 0 0 0 77 0 0 0 % G
% His: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 0 0 77 0 8 0 0 0 8 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % K
% Leu: 8 8 0 16 70 0 24 8 0 0 0 8 0 0 0 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 16 0 0 0 0 8 0 8 % N
% Pro: 0 0 8 0 0 77 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 77 8 0 0 8 0 0 8 8 0 0 0 0 0 % Q
% Arg: 0 0 0 0 8 0 0 8 0 0 0 0 8 0 0 % R
% Ser: 8 0 0 85 0 0 0 62 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 77 8 0 0 8 0 77 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 16 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _