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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: XPO4 All Species: 41.52
Human Site: S737 Identified Species: 76.11
UniProt: Q9C0E2 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9C0E2 NP_071904.4 1151 130139 S737 A K Q F A S R S P P L N F L S
Chimpanzee Pan troglodytes XP_001148853 1150 129990 S736 A K Q F A S R S P P L N F L S
Rhesus Macaque Macaca mulatta XP_001085699 1150 130004 S736 A K Q F A S R S P P L N F L S
Dog Lupus familis XP_534538 1160 131261 S736 A K Q F A S R S P P L N F L S
Cat Felis silvestris
Mouse Mus musculus Q9ESJ0 1151 129947 S737 A K Q F A S R S P P L N F L S
Rat Rattus norvegicus NP_001099512 1148 129647 S734 A K Q F A S R S P P L N Y L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518911 1303 147532 S889 A K Q F A R R S P P L H F L S
Chicken Gallus gallus Q5ZMR9 1154 130298 S740 A K Q F A R R S P P L H Y L S
Frog Xenopus laevis Q499Y0 1150 130077 S736 A K Q F A Q R S P P L N F L S
Zebra Danio Brachydanio rerio Q802D3 1150 129208 S736 A K Q F A S R S P P L H M L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001121681 806 92179 T432 L I P T E I M T Y D M E Q V Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786031 786 88327 S412 Q K Q N G D A S E D D E E E E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_187099 1117 123786 R729 L L S L D S W R N L A N A F A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 99.6 98.8 N.A. 98.5 98 N.A. 85 95.4 93.6 86.6 N.A. N.A. 27.9 N.A. 34.4
Protein Similarity: 100 99.9 99.9 99.1 N.A. 99.3 99.3 N.A. 87.1 98.2 97.3 94 N.A. N.A. 45.3 N.A. 49
P-Site Identity: 100 100 100 100 N.A. 100 93.3 N.A. 86.6 80 93.3 86.6 N.A. N.A. 0 N.A. 20
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 93.3 93.3 93.3 93.3 N.A. N.A. 20 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 27.7 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 49 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 77 0 0 0 77 0 8 0 0 0 8 0 8 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 8 0 0 0 16 8 0 0 0 0 % D
% Glu: 0 0 0 0 8 0 0 0 8 0 0 16 8 8 8 % E
% Phe: 0 0 0 77 0 0 0 0 0 0 0 0 54 8 0 % F
% Gly: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 24 0 0 0 % H
% Ile: 0 8 0 0 0 8 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 85 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 16 8 0 8 0 0 0 0 0 8 77 0 0 77 0 % L
% Met: 0 0 0 0 0 0 8 0 0 0 8 0 8 0 0 % M
% Asn: 0 0 0 8 0 0 0 0 8 0 0 62 0 0 0 % N
% Pro: 0 0 8 0 0 0 0 0 77 77 0 0 0 0 0 % P
% Gln: 8 0 85 0 0 8 0 0 0 0 0 0 8 0 8 % Q
% Arg: 0 0 0 0 0 16 77 8 0 0 0 0 0 0 0 % R
% Ser: 0 0 8 0 0 62 0 85 0 0 0 0 0 0 77 % S
% Thr: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 0 0 16 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _