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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XPO4
All Species:
41.21
Human Site:
Y681
Identified Species:
75.56
UniProt:
Q9C0E2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9C0E2
NP_071904.4
1151
130139
Y681
G
S
Q
W
I
I
G
Y
L
L
Q
K
V
I
S
Chimpanzee
Pan troglodytes
XP_001148853
1150
129990
Y680
G
S
Q
W
I
I
G
Y
L
L
Q
K
V
I
S
Rhesus Macaque
Macaca mulatta
XP_001085699
1150
130004
Y680
G
S
Q
W
I
I
G
Y
L
L
Q
K
V
I
S
Dog
Lupus familis
XP_534538
1160
131261
Y680
G
S
Q
W
I
I
G
Y
L
L
Q
K
V
I
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9ESJ0
1151
129947
Y681
G
S
Q
W
I
I
G
Y
L
L
Q
K
V
I
S
Rat
Rattus norvegicus
NP_001099512
1148
129647
Y678
G
S
Q
W
I
I
G
Y
L
L
Q
K
V
I
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518911
1303
147532
Y833
G
S
Q
W
V
V
G
Y
L
L
E
K
V
I
S
Chicken
Gallus gallus
Q5ZMR9
1154
130298
Y684
G
S
Q
W
I
V
G
Y
L
L
E
K
V
I
S
Frog
Xenopus laevis
Q499Y0
1150
130077
Y680
G
C
H
W
I
I
G
Y
L
L
E
K
V
I
S
Zebra Danio
Brachydanio rerio
Q802D3
1150
129208
Y680
G
A
Q
W
I
V
G
Y
L
L
E
K
V
I
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121681
806
92179
E387
N
K
L
V
E
Q
V
E
S
L
N
T
M
K
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786031
786
88327
S367
Q
L
L
E
C
W
T
S
L
L
R
D
A
G
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_187099
1117
123786
I683
Q
G
K
F
V
L
D
I
I
V
R
I
S
L
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
99.6
98.8
N.A.
98.5
98
N.A.
85
95.4
93.6
86.6
N.A.
N.A.
27.9
N.A.
34.4
Protein Similarity:
100
99.9
99.9
99.1
N.A.
99.3
99.3
N.A.
87.1
98.2
97.3
94
N.A.
N.A.
45.3
N.A.
49
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
80
86.6
80
73.3
N.A.
N.A.
6.6
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
86.6
100
N.A.
N.A.
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% A
% Cys:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% D
% Glu:
0
0
0
8
8
0
0
8
0
0
31
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
77
8
0
0
0
0
77
0
0
0
0
0
0
8
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
70
54
0
8
8
0
0
8
0
77
0
% I
% Lys:
0
8
8
0
0
0
0
0
0
0
0
77
0
8
0
% K
% Leu:
0
8
16
0
0
8
0
0
85
93
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
16
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
16
0
70
0
0
8
0
0
0
0
47
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
0
% R
% Ser:
0
62
0
0
0
0
0
8
8
0
0
0
8
0
70
% S
% Thr:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
8
% T
% Val:
0
0
0
8
16
24
8
0
0
8
0
0
77
0
0
% V
% Trp:
0
0
0
77
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
77
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _