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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LNP All Species: 22.73
Human Site: S114 Identified Species: 35.71
UniProt: Q9C0E8 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9C0E8 NP_085153.1 428 47740 S114 E A L D D L K S Q R K K I L E
Chimpanzee Pan troglodytes XP_515925 402 45566 E102 K R T E R N N E A L D D L K S
Rhesus Macaque Macaca mulatta XP_001091675 620 68101 S306 E A L D D L K S Q R K K I L E
Dog Lupus familis XP_535972 429 47983 S114 E A L D D L K S Q K K K I L E
Cat Felis silvestris
Mouse Mus musculus Q7TQ95 425 47481 S114 E A L D D L K S Q K K K I L E
Rat Rattus norvegicus NP_001070897 376 42151 P79 A R L V M T L P F F A F P L I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515087 443 48921 S114 E A L E D L K S Q K K K I L E
Chicken Gallus gallus XP_421991 419 47301 S114 D A L E D L K S Q K K K I L E
Frog Xenopus laevis Q6DFJ8 440 49749 A114 D A L E L L K A E K K K I L E
Zebra Danio Brachydanio rerio Q6PFM4 402 45200 R104 L F S K R T E R N N D K L E D
Tiger Blowfish Takifugu rubipres Q1KKR9 358 40306 F60 L Y L L I S L F V Y L L Y L P
Fruit Fly Dros. melanogaster NP_610395 387 43619 L90 F P I V I I F L R R L F T W Y
Honey Bee Apis mellifera XP_394179 313 35639 K16 K I S E N E E K L S T M Q L E
Nematode Worm Caenorhab. elegans Q17667 342 38539 M45 N T L Y Y Y Y M S I V V I L S
Sea Urchin Strong. purpuratus XP_787084 392 44052 H95 W L I R K A L H W Y F V K R I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 82.9 66.9 89.9 N.A. 85 75.2 N.A. 72.9 68.4 57 51.6 54.4 29.2 27.1 26.3 36.2
Protein Similarity: 100 85.9 68 93.9 N.A. 89.7 81.5 N.A. 81.4 77 72.2 65.1 64.7 48.5 40.6 45.7 53.7
P-Site Identity: 100 0 100 93.3 N.A. 93.3 13.3 N.A. 86.6 80 60 6.6 13.3 6.6 13.3 20 0
P-Site Similarity: 100 20 100 100 N.A. 100 13.3 N.A. 100 100 93.3 26.6 13.3 26.6 40 20 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 47 0 0 0 7 0 7 7 0 7 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 14 0 0 27 40 0 0 0 0 0 14 7 0 0 7 % D
% Glu: 34 0 0 34 0 7 14 7 7 0 0 0 0 7 54 % E
% Phe: 7 7 0 0 0 0 7 7 7 7 7 14 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % H
% Ile: 0 7 14 0 14 7 0 0 0 7 0 0 54 0 14 % I
% Lys: 14 0 0 7 7 0 47 7 0 34 47 54 7 7 0 % K
% Leu: 14 7 67 7 7 47 20 7 7 7 14 7 14 74 0 % L
% Met: 0 0 0 0 7 0 0 7 0 0 0 7 0 0 0 % M
% Asn: 7 0 0 0 7 7 7 0 7 7 0 0 0 0 0 % N
% Pro: 0 7 0 0 0 0 0 7 0 0 0 0 7 0 7 % P
% Gln: 0 0 0 0 0 0 0 0 40 0 0 0 7 0 0 % Q
% Arg: 0 14 0 7 14 0 0 7 7 20 0 0 0 7 0 % R
% Ser: 0 0 14 0 0 7 0 40 7 7 0 0 0 0 14 % S
% Thr: 0 7 7 0 0 14 0 0 0 0 7 0 7 0 0 % T
% Val: 0 0 0 14 0 0 0 0 7 0 7 14 0 0 0 % V
% Trp: 7 0 0 0 0 0 0 0 7 0 0 0 0 7 0 % W
% Tyr: 0 7 0 7 7 7 7 0 0 14 0 0 7 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _