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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LNP All Species: 17.58
Human Site: S194 Identified Species: 27.62
UniProt: Q9C0E8 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9C0E8 NP_085153.1 428 47740 S194 P P P Q V P V S P G P P K D S
Chimpanzee Pan troglodytes XP_515925 402 45566 P182 P A S P N Q G P P P Q V P V S
Rhesus Macaque Macaca mulatta XP_001091675 620 68101 S386 P P P Q V P V S P G P P K D S
Dog Lupus familis XP_535972 429 47983 S194 P P P Q V P V S P G P P K D S
Cat Felis silvestris
Mouse Mus musculus Q7TQ95 425 47481 S194 P P P Q G P V S P G P A K D A
Rat Rattus norvegicus NP_001070897 376 42151 T159 P S A G A A A T A K P G Q E I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515087 443 48921 P194 G T P P P P P P P P P V P G S
Chicken Gallus gallus XP_421991 419 47301 S194 S P K L L V S S T P S P D L Q
Frog Xenopus laevis Q6DFJ8 440 49749 L194 G S P Q V S G L L A A T P A L
Zebra Danio Brachydanio rerio Q6PFM4 402 45200 S184 G P V L G P M S P G T T P L R
Tiger Blowfish Takifugu rubipres Q1KKR9 358 40306 D140 K A I L E R F D P D A K K K P
Fruit Fly Dros. melanogaster NP_610395 387 43619 A170 R S P L T V A A V A R T S S A
Honey Bee Apis mellifera XP_394179 313 35639 P96 V I T S Q N Q P L N L Q S G T
Nematode Worm Caenorhab. elegans Q17667 342 38539 K125 V K E T L K F K E A K E I L D
Sea Urchin Strong. purpuratus XP_787084 392 44052 G175 Q R P F S A R G R G R G R G S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 82.9 66.9 89.9 N.A. 85 75.2 N.A. 72.9 68.4 57 51.6 54.4 29.2 27.1 26.3 36.2
Protein Similarity: 100 85.9 68 93.9 N.A. 89.7 81.5 N.A. 81.4 77 72.2 65.1 64.7 48.5 40.6 45.7 53.7
P-Site Identity: 100 20 100 100 N.A. 80 13.3 N.A. 33.3 20 20 33.3 13.3 6.6 0 0 20
P-Site Similarity: 100 20 100 100 N.A. 86.6 33.3 N.A. 33.3 26.6 20 40 13.3 20 6.6 6.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 14 7 0 7 14 14 7 7 20 14 7 0 7 14 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 7 0 7 0 0 7 27 7 % D
% Glu: 0 0 7 0 7 0 0 0 7 0 0 7 0 7 0 % E
% Phe: 0 0 0 7 0 0 14 0 0 0 0 0 0 0 0 % F
% Gly: 20 0 0 7 14 0 14 7 0 40 0 14 0 20 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 7 0 0 0 0 0 0 0 0 0 7 0 7 % I
% Lys: 7 7 7 0 0 7 0 7 0 7 7 7 34 7 0 % K
% Leu: 0 0 0 27 14 0 0 7 14 0 7 0 0 20 7 % L
% Met: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 7 7 0 0 0 7 0 0 0 0 0 % N
% Pro: 40 40 54 14 7 40 7 20 54 20 40 27 27 0 7 % P
% Gln: 7 0 0 34 7 7 7 0 0 0 7 7 7 0 7 % Q
% Arg: 7 7 0 0 0 7 7 0 7 0 14 0 7 0 7 % R
% Ser: 7 20 7 7 7 7 7 40 0 0 7 0 14 7 40 % S
% Thr: 0 7 7 7 7 0 0 7 7 0 7 20 0 0 7 % T
% Val: 14 0 7 0 27 14 27 0 7 0 0 14 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _