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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LNP All Species: 7.27
Human Site: S217 Identified Species: 11.43
UniProt: Q9C0E8 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9C0E8 NP_085153.1 428 47740 S217 R T V T P A L S S N V L P R H
Chimpanzee Pan troglodytes XP_515925 402 45566 R205 A P G G P P E R T V T P A L S
Rhesus Macaque Macaca mulatta XP_001091675 620 68101 P409 R T V T P A L P S N V L P R H
Dog Lupus familis XP_535972 429 47983 S217 R T V T P A L S S N V L P R R
Cat Felis silvestris
Mouse Mus musculus Q7TQ95 425 47481 P217 R T V A P A L P R R L G S P A
Rat Rattus norvegicus NP_001070897 376 42151 N182 N L S P A P A N S N Q G P P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515087 443 48921 R217 A P G G P P D R A I A T A L Q
Chicken Gallus gallus XP_421991 419 47301 P217 P P E R T A V P S L Q S N V L
Frog Xenopus laevis Q6DFJ8 440 49749 Q217 G P P E R S V Q P T P Q S N I
Zebra Danio Brachydanio rerio Q6PFM4 402 45200 S207 K G L A G S A S T P A G A S Q
Tiger Blowfish Takifugu rubipres Q1KKR9 358 40306 G163 P Q M T P G A G Q E L R Q R G
Fruit Fly Dros. melanogaster NP_610395 387 43619 V193 S L A P Y T S V Y R N N N N N
Honey Bee Apis mellifera XP_394179 313 35639 N119 V G I T P T Q N P S N A S F Q
Nematode Worm Caenorhab. elegans Q17667 342 38539 S148 T T I D K N D S T L K S P S P
Sea Urchin Strong. purpuratus XP_787084 392 44052 P198 S A R L G N Q P M L Q S P Q A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 82.9 66.9 89.9 N.A. 85 75.2 N.A. 72.9 68.4 57 51.6 54.4 29.2 27.1 26.3 36.2
Protein Similarity: 100 85.9 68 93.9 N.A. 89.7 81.5 N.A. 81.4 77 72.2 65.1 64.7 48.5 40.6 45.7 53.7
P-Site Identity: 100 6.6 93.3 93.3 N.A. 40 20 N.A. 6.6 13.3 0 6.6 20 0 13.3 20 6.6
P-Site Similarity: 100 13.3 93.3 93.3 N.A. 46.6 26.6 N.A. 13.3 20 13.3 33.3 33.3 6.6 33.3 33.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 7 7 14 7 34 20 0 7 0 14 7 20 0 14 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 7 0 0 14 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 7 7 0 0 7 0 0 7 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % F
% Gly: 7 14 14 14 14 7 0 7 0 0 0 20 0 0 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14 % H
% Ile: 0 0 14 0 0 0 0 0 0 7 0 0 0 0 7 % I
% Lys: 7 0 0 0 7 0 0 0 0 0 7 0 0 0 0 % K
% Leu: 0 14 7 7 0 0 27 0 0 20 14 20 0 14 7 % L
% Met: 0 0 7 0 0 0 0 0 7 0 0 0 0 0 0 % M
% Asn: 7 0 0 0 0 14 0 14 0 27 14 7 14 14 7 % N
% Pro: 14 27 7 14 54 20 0 27 14 7 7 7 40 14 14 % P
% Gln: 0 7 0 0 0 0 14 7 7 0 20 7 7 7 20 % Q
% Arg: 27 0 7 7 7 0 0 14 7 14 0 7 0 27 7 % R
% Ser: 14 0 7 0 0 14 7 27 34 7 0 20 20 14 7 % S
% Thr: 7 34 0 34 7 14 0 0 20 7 7 7 0 0 0 % T
% Val: 7 0 27 0 0 0 14 7 0 7 20 0 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 0 0 0 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _