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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LNP All Species: 20.3
Human Site: S321 Identified Species: 31.9
UniProt: Q9C0E8 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9C0E8 NP_085153.1 428 47740 S321 A P R L P E F S F E K R Q V V
Chimpanzee Pan troglodytes XP_515925 402 45566 A294 E Y I A F R C A Y C F F L N P
Rhesus Macaque Macaca mulatta XP_001091675 620 68101 S513 A P R L P E F S F E K R Q M V
Dog Lupus familis XP_535972 429 47983 S321 A P R L P E F S F E K R Q A V
Cat Felis silvestris
Mouse Mus musculus Q7TQ95 425 47481 S316 A P R L P E F S F E K R Q A V
Rat Rattus norvegicus NP_001070897 376 42151 I270 P Q N R Y A L I C Q Q C F S H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515087 443 48921 S328 A P R L P D F S F E K K S S I
Chicken Gallus gallus XP_421991 419 47301 R311 C F F L N P A R K T R P R A P
Frog Xenopus laevis Q6DFJ8 440 49749 S325 A P R L Q E I S F D R Q R Q R
Zebra Danio Brachydanio rerio Q6PFM4 402 45200 A295 K E E F E F V A F R C A Y C Y
Tiger Blowfish Takifugu rubipres Q1KKR9 358 40306 R252 R P V L P K D R G A V D R V I
Fruit Fly Dros. melanogaster NP_610395 387 43619 E281 H N G M L P K E E Y E Y T T F
Honey Bee Apis mellifera XP_394179 313 35639 R207 C N F W N P A R K Q K P S I P
Nematode Worm Caenorhab. elegans Q17667 342 38539 C236 N C R N A L I C S I C H T H N
Sea Urchin Strong. purpuratus XP_787084 392 44052 L286 V R P N A P K L P E T P A V A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 82.9 66.9 89.9 N.A. 85 75.2 N.A. 72.9 68.4 57 51.6 54.4 29.2 27.1 26.3 36.2
Protein Similarity: 100 85.9 68 93.9 N.A. 89.7 81.5 N.A. 81.4 77 72.2 65.1 64.7 48.5 40.6 45.7 53.7
P-Site Identity: 100 0 93.3 93.3 N.A. 93.3 0 N.A. 66.6 6.6 46.6 6.6 26.6 0 6.6 6.6 13.3
P-Site Similarity: 100 13.3 100 93.3 N.A. 93.3 13.3 N.A. 86.6 20 73.3 13.3 46.6 13.3 20 6.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 40 0 0 7 14 7 14 14 0 7 0 7 7 20 7 % A
% Cys: 14 7 0 0 0 0 7 7 7 7 14 7 0 7 0 % C
% Asp: 0 0 0 0 0 7 7 0 0 7 0 7 0 0 0 % D
% Glu: 7 7 7 0 7 34 0 7 7 40 7 0 0 0 0 % E
% Phe: 0 7 14 7 7 7 34 0 47 0 7 7 7 0 7 % F
% Gly: 0 0 7 0 0 0 0 0 7 0 0 0 0 0 0 % G
% His: 7 0 0 0 0 0 0 0 0 0 0 7 0 7 7 % H
% Ile: 0 0 7 0 0 0 14 7 0 7 0 0 0 7 14 % I
% Lys: 7 0 0 0 0 7 14 0 14 0 40 7 0 0 0 % K
% Leu: 0 0 0 54 7 7 7 7 0 0 0 0 7 0 0 % L
% Met: 0 0 0 7 0 0 0 0 0 0 0 0 0 7 0 % M
% Asn: 7 14 7 14 14 0 0 0 0 0 0 0 0 7 7 % N
% Pro: 7 47 7 0 40 27 0 0 7 0 0 20 0 0 20 % P
% Gln: 0 7 0 0 7 0 0 0 0 14 7 7 27 7 0 % Q
% Arg: 7 7 47 7 0 7 0 20 0 7 14 27 20 0 7 % R
% Ser: 0 0 0 0 0 0 0 40 7 0 0 0 14 14 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 7 7 0 14 7 0 % T
% Val: 7 0 7 0 0 0 7 0 0 0 7 0 0 20 27 % V
% Trp: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 7 0 0 0 7 7 0 7 7 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _