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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LNP All Species: 13.64
Human Site: S333 Identified Species: 21.43
UniProt: Q9C0E8 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9C0E8 NP_085153.1 428 47740 S333 Q V V E G S S S V G P L P S G
Chimpanzee Pan troglodytes XP_515925 402 45566 R306 L N P A R K T R P Q A P R L P
Rhesus Macaque Macaca mulatta XP_001091675 620 68101 S525 Q M V E G S S S V G P L P S G
Dog Lupus familis XP_535972 429 47983 S333 Q A V E S S S S L G P L P S G
Cat Felis silvestris
Mouse Mus musculus Q7TQ95 425 47481 S328 Q A V E G S S S T G P T L L E
Rat Rattus norvegicus NP_001070897 376 42151 L282 F S H N G M A L K E E F E Y I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515087 443 48921 S340 S S I E G P S S I G S L Q L E
Chicken Gallus gallus XP_421991 419 47301 F323 R A P R L P D F N F E K K Q L
Frog Xenopus laevis Q6DFJ8 440 49749 G337 R Q R T D S Q G S V N T L Q L
Zebra Danio Brachydanio rerio Q6PFM4 402 45200 A307 Y C Y F M N P A R K T R P Q A
Tiger Blowfish Takifugu rubipres Q1KKR9 358 40306 G264 R V I E Y L V G D G P Q N R Y
Fruit Fly Dros. melanogaster NP_610395 387 43619 C293 T T F R C A F C N V L N P A R
Honey Bee Apis mellifera XP_394179 313 35639 N219 S I P K P E C N V G F S S P S
Nematode Worm Caenorhab. elegans Q17667 342 38539 P248 T H N G M S T P A E Y P Y I S
Sea Urchin Strong. purpuratus XP_787084 392 44052 L298 A V A F G A R L V D P E R R G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 82.9 66.9 89.9 N.A. 85 75.2 N.A. 72.9 68.4 57 51.6 54.4 29.2 27.1 26.3 36.2
Protein Similarity: 100 85.9 68 93.9 N.A. 89.7 81.5 N.A. 81.4 77 72.2 65.1 64.7 48.5 40.6 45.7 53.7
P-Site Identity: 100 0 93.3 80 N.A. 60 6.6 N.A. 40 0 6.6 6.6 26.6 6.6 13.3 6.6 33.3
P-Site Similarity: 100 6.6 100 86.6 N.A. 60 13.3 N.A. 53.3 6.6 13.3 20 40 20 33.3 13.3 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 20 7 7 0 14 7 7 7 0 7 0 0 7 7 % A
% Cys: 0 7 0 0 7 0 7 7 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 7 0 7 0 7 7 0 0 0 0 0 % D
% Glu: 0 0 0 40 0 7 0 0 0 14 14 7 7 0 14 % E
% Phe: 7 0 7 14 0 0 7 7 0 7 7 7 0 0 0 % F
% Gly: 0 0 0 7 40 0 0 14 0 47 0 0 0 0 27 % G
% His: 0 7 7 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 14 0 0 0 0 0 7 0 0 0 0 7 7 % I
% Lys: 0 0 0 7 0 7 0 0 7 7 0 7 7 0 0 % K
% Leu: 7 0 0 0 7 7 0 14 7 0 7 27 14 20 14 % L
% Met: 0 7 0 0 14 7 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 7 7 7 0 7 0 7 14 0 7 7 7 0 0 % N
% Pro: 0 0 20 0 7 14 7 7 7 0 40 14 34 7 7 % P
% Gln: 27 7 0 0 0 0 7 0 0 7 0 7 7 20 0 % Q
% Arg: 20 0 7 14 7 0 7 7 7 0 0 7 14 14 7 % R
% Ser: 14 14 0 0 7 40 34 34 7 0 7 7 7 20 14 % S
% Thr: 14 7 0 7 0 0 14 0 7 0 7 14 0 0 0 % T
% Val: 0 20 27 0 0 0 7 0 27 14 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 7 0 7 0 0 0 0 0 7 0 7 7 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _