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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LNP All Species: 7.88
Human Site: S401 Identified Species: 12.38
UniProt: Q9C0E8 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.36
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9C0E8 NP_085153.1 428 47740 S401 E T E N E E A S V I E T N S T
Chimpanzee Pan troglodytes XP_515925 402 45566 G374 W K V F I K G G D L E E I S L
Rhesus Macaque Macaca mulatta XP_001091675 620 68101 S593 E T E N E E A S V I E A N S T
Dog Lupus familis XP_535972 429 47983 T401 Q E A E N E D T S M N E A K S
Cat Felis silvestris
Mouse Mus musculus Q7TQ95 425 47481 E396 Q E E T E N E E T S T N E A K
Rat Rattus norvegicus NP_001070897 376 42151 I350 Q L T E G G T I P Q M S H F L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515087 443 48921 E408 A E E A E N E E T T Q V E A K
Chicken Gallus gallus XP_421991 419 47301 A391 E E V E K E A A E N V S T T E
Frog Xenopus laevis Q6DFJ8 440 49749 E405 C S E Q Q W E E A P D D T E K
Zebra Danio Brachydanio rerio Q6PFM4 402 45200 E375 A P V L Q E S E T E E S Q P Q
Tiger Blowfish Takifugu rubipres Q1KKR9 358 40306 P332 L R A E S S T P G P A P H S A
Fruit Fly Dros. melanogaster NP_610395 387 43619 T361 D M D A T A E T E D L A M E T
Honey Bee Apis mellifera XP_394179 313 35639 E287 K S Y D E R N E P E K L E T K
Nematode Worm Caenorhab. elegans Q17667 342 38539 S316 T D L T P S A S Q N G S E K G
Sea Urchin Strong. purpuratus XP_787084 392 44052 A366 E E T I E D E A G D H I D V T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 82.9 66.9 89.9 N.A. 85 75.2 N.A. 72.9 68.4 57 51.6 54.4 29.2 27.1 26.3 36.2
Protein Similarity: 100 85.9 68 93.9 N.A. 89.7 81.5 N.A. 81.4 77 72.2 65.1 64.7 48.5 40.6 45.7 53.7
P-Site Identity: 100 13.3 93.3 6.6 N.A. 13.3 0 N.A. 13.3 20 6.6 13.3 6.6 6.6 6.6 13.3 20
P-Site Similarity: 100 26.6 93.3 33.3 N.A. 26.6 20 N.A. 26.6 46.6 26.6 33.3 13.3 26.6 40 20 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 0 14 14 0 7 27 14 7 0 7 14 7 14 7 % A
% Cys: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 7 7 7 0 7 7 0 7 14 7 7 7 0 0 % D
% Glu: 27 34 34 27 40 34 34 34 14 14 27 14 27 14 7 % E
% Phe: 0 0 0 7 0 0 0 0 0 0 0 0 0 7 0 % F
% Gly: 0 0 0 0 7 7 7 7 14 0 7 0 0 0 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 7 0 14 0 0 % H
% Ile: 0 0 0 7 7 0 0 7 0 14 0 7 7 0 0 % I
% Lys: 7 7 0 0 7 7 0 0 0 0 7 0 0 14 27 % K
% Leu: 7 7 7 7 0 0 0 0 0 7 7 7 0 0 14 % L
% Met: 0 7 0 0 0 0 0 0 0 7 7 0 7 0 0 % M
% Asn: 0 0 0 14 7 14 7 0 0 14 7 7 14 0 0 % N
% Pro: 0 7 0 0 7 0 0 7 14 14 0 7 0 7 0 % P
% Gln: 20 0 0 7 14 0 0 0 7 7 7 0 7 0 7 % Q
% Arg: 0 7 0 0 0 7 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 14 0 0 7 14 7 20 7 7 0 27 0 27 7 % S
% Thr: 7 14 14 14 7 0 14 14 20 7 7 7 14 14 27 % T
% Val: 0 0 20 0 0 0 0 0 14 0 7 7 0 7 0 % V
% Trp: 7 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _