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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LNP All Species: 8.79
Human Site: S414 Identified Species: 13.81
UniProt: Q9C0E8 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.36
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9C0E8 NP_085153.1 428 47740 S414 S T V P G A D S I P D P E L S
Chimpanzee Pan troglodytes XP_515925 402 45566 E387 S L I N F S P E Y L E Y F F L
Rhesus Macaque Macaca mulatta XP_001091675 620 68101 S606 S T V P G A D S I P D P E L S
Dog Lupus familis XP_535972 429 47983 D414 K S V V P R A D P I P N P E L
Cat Felis silvestris
Mouse Mus musculus Q7TQ95 425 47481 A409 A K S P V L R A D S V P N L E
Rat Rattus norvegicus NP_001070897 376 42151 M363 F L S E I S G M K S N W L K V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515087 443 48921 V421 A K S T A T N V D S A A A A A
Chicken Gallus gallus XP_421991 419 47301 S404 T E D S I S D S A I S T E Q S
Frog Xenopus laevis Q6DFJ8 440 49749 A418 E K D N L P A A E V N P S L P
Zebra Danio Brachydanio rerio Q6PFM4 402 45200 E388 P Q D V P H A E A E A L E E Q
Tiger Blowfish Takifugu rubipres Q1KKR9 358 40306 S345 S A T D T E E S A P P S R G M
Fruit Fly Dros. melanogaster NP_610395 387 43619 G374 E T E T I E T G S A A P S T A
Honey Bee Apis mellifera XP_394179 313 35639 E300 T K E E Q N Y E E S V E K M D
Nematode Worm Caenorhab. elegans Q17667 342 38539 E329 K G S D S E N E K V P E S K T
Sea Urchin Strong. purpuratus XP_787084 392 44052 T379 V T E S T T E T P E R N E A P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 82.9 66.9 89.9 N.A. 85 75.2 N.A. 72.9 68.4 57 51.6 54.4 29.2 27.1 26.3 36.2
Protein Similarity: 100 85.9 68 93.9 N.A. 89.7 81.5 N.A. 81.4 77 72.2 65.1 64.7 48.5 40.6 45.7 53.7
P-Site Identity: 100 6.6 100 6.6 N.A. 20 0 N.A. 0 26.6 13.3 6.6 20 13.3 0 0 13.3
P-Site Similarity: 100 26.6 100 13.3 N.A. 33.3 13.3 N.A. 20 40 26.6 6.6 26.6 20 20 13.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 7 0 0 7 14 20 14 20 7 20 7 7 14 14 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 20 14 0 0 20 7 14 0 14 0 0 0 7 % D
% Glu: 14 7 20 14 0 20 14 27 14 14 7 14 34 14 7 % E
% Phe: 7 0 0 0 7 0 0 0 0 0 0 0 7 7 0 % F
% Gly: 0 7 0 0 14 0 7 7 0 0 0 0 0 7 0 % G
% His: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 7 0 20 0 0 0 14 14 0 0 0 0 0 % I
% Lys: 14 27 0 0 0 0 0 0 14 0 0 0 7 14 0 % K
% Leu: 0 14 0 0 7 7 0 0 0 7 0 7 7 27 14 % L
% Met: 0 0 0 0 0 0 0 7 0 0 0 0 0 7 7 % M
% Asn: 0 0 0 14 0 7 14 0 0 0 14 14 7 0 0 % N
% Pro: 7 0 0 20 14 7 7 0 14 20 20 34 7 0 14 % P
% Gln: 0 7 0 0 7 0 0 0 0 0 0 0 0 7 7 % Q
% Arg: 0 0 0 0 0 7 7 0 0 0 7 0 7 0 0 % R
% Ser: 27 7 27 14 7 20 0 27 7 27 7 7 20 0 20 % S
% Thr: 14 27 7 14 14 14 7 7 0 0 0 7 0 7 7 % T
% Val: 7 0 20 14 7 0 0 7 0 14 14 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % W
% Tyr: 0 0 0 0 0 0 7 0 7 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _