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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LNP
All Species:
6.61
Human Site:
S424
Identified Species:
10.39
UniProt:
Q9C0E8
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9C0E8
NP_085153.1
428
47740
S424
D
P
E
L
S
G
E
S
L
T
A
E
_
_
_
Chimpanzee
Pan troglodytes
XP_515925
402
45566
Y397
E
Y
F
F
L
E
F
Y
I
Q
M
L
W
_
_
Rhesus Macaque
Macaca mulatta
XP_001091675
620
68101
Y616
D
P
E
L
S
G
E
Y
L
T
A
E
_
_
_
Dog
Lupus familis
XP_535972
429
47983
E424
P
N
P
E
L
S
G
E
S
L
M
A
M
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q7TQ95
425
47481
E419
V
P
N
L
E
P
S
E
E
S
L
V
T
K
_
Rat
Rattus norvegicus
NP_001070897
376
42151
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515087
443
48921
A431
A
A
A
A
A
A
A
A
S
E
L
S
G
E
T
Chicken
Gallus gallus
XP_421991
419
47301
S414
S
T
E
Q
S
E
E
S
L
V
K
A
E
_
_
Frog
Xenopus laevis
Q6DFJ8
440
49749
A428
N
P
S
L
P
A
P
A
A
N
E
S
E
E
S
Zebra Danio
Brachydanio rerio
Q6PFM4
402
45200
E398
A
L
E
E
Q
K
K
E
D
E
S
N
_
_
_
Tiger Blowfish
Takifugu rubipres
Q1KKR9
358
40306
Fruit Fly
Dros. melanogaster
NP_610395
387
43619
Honey Bee
Apis mellifera
XP_394179
313
35639
Nematode Worm
Caenorhab. elegans
Q17667
342
38539
Sea Urchin
Strong. purpuratus
XP_787084
392
44052
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.9
66.9
89.9
N.A.
85
75.2
N.A.
72.9
68.4
57
51.6
54.4
29.2
27.1
26.3
36.2
Protein Similarity:
100
85.9
68
93.9
N.A.
89.7
81.5
N.A.
81.4
77
72.2
65.1
64.7
48.5
40.6
45.7
53.7
P-Site Identity:
100
0
91.6
0
N.A.
14.2
0
N.A.
0
38.4
13.3
8.3
0
0
0
0
0
P-Site Similarity:
100
15.3
91.6
0
N.A.
21.4
0
N.A.
20
38.4
26.6
25
0
0
0
0
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
7
7
7
7
14
7
14
7
0
14
14
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% D
% Glu:
7
0
27
14
7
14
20
20
7
14
7
14
14
14
0
% E
% Phe:
0
0
7
7
0
0
7
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
14
7
0
0
0
0
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
7
7
0
0
0
7
0
0
7
0
% K
% Leu:
0
7
0
27
14
0
0
0
20
7
14
7
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
14
0
7
0
0
% M
% Asn:
7
7
7
0
0
0
0
0
0
7
0
7
0
0
0
% N
% Pro:
7
27
7
0
7
7
7
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
7
7
0
0
0
0
7
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
7
0
7
0
20
7
7
14
14
7
7
14
0
0
7
% S
% Thr:
0
7
0
0
0
0
0
0
0
14
0
0
7
0
7
% T
% Val:
7
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
7
0
0
0
0
0
14
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
20
40
47
% _