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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ASXL3
All Species:
11.52
Human Site:
S296
Identified Species:
31.67
UniProt:
Q9C0F0
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9C0F0
NP_085135.1
2248
241919
S296
E
V
D
R
Q
M
G
S
D
G
I
L
R
L
S
Chimpanzee
Pan troglodytes
XP_524003
2197
236734
Y288
L
N
N
E
F
F
A
Y
A
A
Q
G
W
K
Q
Rhesus Macaque
Macaca mulatta
XP_001101495
2249
242361
S296
E
V
D
R
Q
M
G
S
D
G
I
L
R
L
S
Dog
Lupus familis
XP_853069
2156
231578
T293
G
A
E
S
S
C
G
T
S
G
L
P
G
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8C4A5
2259
243654
S295
E
V
D
R
Q
M
G
S
D
G
I
L
R
L
S
Rat
Rattus norvegicus
XP_002726316
1480
158368
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515168
1882
199357
R51
H
R
R
V
P
G
Q
R
L
L
S
E
R
A
G
Chicken
Gallus gallus
Q5ZM88
1412
148651
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001341242
1619
172271
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.9
96.7
85
N.A.
81.6
24.3
N.A.
49.9
24.3
N.A.
26
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97.3
98.1
89.8
N.A.
88.7
37.6
N.A.
60.8
38.1
N.A.
40.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
26.6
N.A.
100
0
N.A.
6.6
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
100
46.6
N.A.
100
0
N.A.
6.6
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
0
0
0
12
0
12
12
0
0
0
12
0
% A
% Cys:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
34
0
0
0
0
0
34
0
0
0
0
0
0
% D
% Glu:
34
0
12
12
0
0
0
0
0
0
0
12
0
0
0
% E
% Phe:
0
0
0
0
12
12
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
0
0
0
0
12
45
0
0
45
0
12
12
0
12
% G
% His:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
34
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% K
% Leu:
12
0
0
0
0
0
0
0
12
12
12
34
0
45
0
% L
% Met:
0
0
0
0
0
34
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
12
12
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
12
0
0
0
0
0
0
12
0
0
0
% P
% Gln:
0
0
0
0
34
0
12
0
0
0
12
0
0
0
12
% Q
% Arg:
0
12
12
34
0
0
0
12
0
0
0
0
45
0
0
% R
% Ser:
0
0
0
12
12
0
0
34
12
0
12
0
0
0
45
% S
% Thr:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% T
% Val:
0
34
0
12
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% W
% Tyr:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _