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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIAA1712 All Species: 4.24
Human Site: S253 Identified Species: 9.33
UniProt: Q9C0F1 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9C0F1 NP_001035247.1 390 44140 S253 E N L K K L T S I E K R L D C
Chimpanzee Pan troglodytes XP_001156603 390 44107 S253 E N L K K L T S I E K R L A C
Rhesus Macaque Macaca mulatta XP_001086282 390 44031 L253 E K L K E L T L I E K R L D C
Dog Lupus familis XP_534555 373 42606 E242 A L Q T M L T E C Q E K L Q K
Cat Felis silvestris
Mouse Mus musculus Q5HZK1 386 43237 W252 E K L K Q L T W I E K R L E R
Rat Rattus norvegicus Q3B7T8 386 43248 W252 E K L K K L T W I E K R L E C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506210 395 44804 A260 E F S T Q I A A L Q R G L V E
Chicken Gallus gallus XP_420525 395 44883 W249 E K L H K L D W M E D K L R V
Frog Xenopus laevis A2RVA7 384 43486 C244 E K L Q R L D C V E Q R L Q S
Zebra Danio Brachydanio rerio NP_001070204 211 23743 R82 E N V Y K V L R D V F S Y K P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785702 157 18183 F28 K Y P K D L D F T S L A R G A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 94 75.9 N.A. 66.4 69.2 N.A. 44.5 46.8 47.1 28.7 N.A. N.A. N.A. N.A. 21.5
Protein Similarity: 100 99.4 97.6 85.9 N.A. 76.6 79.4 N.A. 60.5 64.8 64.3 41 N.A. N.A. N.A. N.A. 30
P-Site Identity: 100 93.3 80 20 N.A. 66.6 80 N.A. 13.3 40 40 20 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 93.3 86.6 40 N.A. 80 86.6 N.A. 53.3 53.3 66.6 33.3 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 10 10 0 0 0 10 0 10 10 % A
% Cys: 0 0 0 0 0 0 0 10 10 0 0 0 0 0 37 % C
% Asp: 0 0 0 0 10 0 28 0 10 0 10 0 0 19 0 % D
% Glu: 82 0 0 0 10 0 0 10 0 64 10 0 0 19 10 % E
% Phe: 0 10 0 0 0 0 0 10 0 0 10 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 10 0 10 0 % G
% His: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 10 0 0 46 0 0 0 0 0 0 % I
% Lys: 10 46 0 55 46 0 0 0 0 0 46 19 0 10 10 % K
% Leu: 0 10 64 0 0 82 10 10 10 0 10 0 82 0 0 % L
% Met: 0 0 0 0 10 0 0 0 10 0 0 0 0 0 0 % M
% Asn: 0 28 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 10 % P
% Gln: 0 0 10 10 19 0 0 0 0 19 10 0 0 19 0 % Q
% Arg: 0 0 0 0 10 0 0 10 0 0 10 55 10 10 10 % R
% Ser: 0 0 10 0 0 0 0 19 0 10 0 10 0 0 10 % S
% Thr: 0 0 0 19 0 0 55 0 10 0 0 0 0 0 0 % T
% Val: 0 0 10 0 0 10 0 0 10 10 0 0 0 10 10 % V
% Trp: 0 0 0 0 0 0 0 28 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 10 0 0 0 0 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _