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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTYH3
All Species:
13.64
Human Site:
S445
Identified Species:
33.33
UniProt:
Q9C0H2
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9C0H2
NP_079526.1
523
57545
S445
L
Y
R
V
H
M
P
S
L
Y
S
C
G
S
S
Chimpanzee
Pan troglodytes
XP_001168124
534
58729
R452
P
P
R
G
Q
L
H
R
F
C
S
Y
S
S
G
Rhesus Macaque
Macaca mulatta
XP_001103727
399
44376
K322
P
S
E
Q
P
A
T
K
D
P
L
L
R
V
Q
Dog
Lupus familis
XP_547008
579
63885
P500
S
S
I
V
C
S
V
P
H
T
W
Q
Q
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q6P5F7
524
57695
S445
L
Y
R
V
H
M
P
S
L
Y
S
C
G
S
S
Rat
Rattus norvegicus
P0C5X8
450
49014
L373
A
L
L
H
C
R
S
L
H
K
D
Y
G
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513420
642
71454
S446
L
Y
R
V
H
M
P
S
L
Y
S
C
G
S
S
Chicken
Gallus gallus
XP_414776
509
56810
S431
L
Y
R
V
H
M
P
S
L
Y
S
C
G
S
S
Frog
Xenopus laevis
Q6GPA5
522
58963
N438
G
T
R
Q
T
H
D
N
L
Y
R
V
H
M
P
Zebra Danio
Brachydanio rerio
Q32LT7
560
62173
L448
Y
R
V
H
M
P
S
L
Y
S
C
G
S
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39.3
74.3
77.5
N.A.
94.6
34.7
N.A.
66.6
72.4
73
66.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
57.4
74.9
79.9
N.A.
96.1
49.7
N.A.
72.7
81.4
82.4
76.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
20
0
6.6
N.A.
100
13.3
N.A.
100
100
20
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
0
6.6
N.A.
100
20
N.A.
100
100
26.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
20
0
0
0
0
10
10
40
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
10
0
10
0
0
0
0
% D
% Glu:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
10
0
0
10
0
0
0
0
0
0
0
10
50
0
10
% G
% His:
0
0
0
20
40
10
10
0
20
0
0
0
10
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
10
0
0
0
10
0
% K
% Leu:
40
10
10
0
0
10
0
20
50
0
10
10
0
0
0
% L
% Met:
0
0
0
0
10
40
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
20
10
0
0
10
10
40
10
0
10
0
0
0
0
10
% P
% Gln:
0
0
0
20
10
0
0
0
0
0
0
10
10
0
10
% Q
% Arg:
0
10
60
0
0
10
0
10
0
0
10
0
10
0
10
% R
% Ser:
10
20
0
0
0
10
20
40
0
10
50
0
20
70
40
% S
% Thr:
0
10
0
0
10
0
10
0
0
10
0
0
0
0
10
% T
% Val:
0
0
10
50
0
0
10
0
0
0
0
10
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
10
40
0
0
0
0
0
0
10
50
0
20
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _