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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL4
All Species:
1.52
Human Site:
S109
Identified Species:
3.03
UniProt:
Q9C0H6
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9C0H6
NP_061990.2
718
80245
S109
A
N
E
D
T
P
K
S
V
P
E
K
N
L
F
Chimpanzee
Pan troglodytes
XP_517151
841
93132
A217
N
S
P
S
W
P
M
A
S
T
S
E
V
P
A
Rhesus Macaque
Macaca mulatta
XP_001083897
666
74374
N90
A
H
Q
R
A
V
Q
N
L
Q
Q
H
N
L
I
Dog
Lupus familis
XP_549119
657
73569
L81
T
E
D
S
T
A
R
L
D
T
Q
N
P
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9JI74
751
82914
T134
S
L
E
E
E
V
V
T
G
M
D
F
P
G
P
Rat
Rattus norvegicus
Q8K430
640
69714
C90
M
R
Q
R
G
L
L
C
D
I
V
L
H
V
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512881
889
97747
A267
N
S
S
P
W
P
M
A
A
P
S
E
V
P
P
Chicken
Gallus gallus
XP_420250
720
80554
E109
S
N
E
D
I
P
K
E
N
T
E
E
N
C
V
Frog
Xenopus laevis
Q6NRH0
564
63190
V31
K
S
Q
T
L
C
D
V
T
L
R
V
N
L
K
Zebra Danio
Brachydanio rerio
Q5U374
564
62914
I31
K
S
N
T
L
C
D
I
T
L
R
V
E
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
R87
G
R
K
I
F
A
H
R
V
I
L
S
A
C
S
Honey Bee
Apis mellifera
XP_624257
612
67322
H79
I
L
I
A
G
K
R
H
I
P
A
H
R
L
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55.2
91
81.8
N.A.
65.2
37.1
N.A.
53
83
31.7
31.4
N.A.
37.4
52.9
N.A.
N.A.
Protein Similarity:
100
67.1
92.1
86.3
N.A.
77.5
53
N.A.
64.3
89
47.6
46.5
N.A.
53.4
66
N.A.
N.A.
P-Site Identity:
100
6.6
20
6.6
N.A.
6.6
0
N.A.
13.3
46.6
13.3
0
N.A.
6.6
13.3
N.A.
N.A.
P-Site Similarity:
100
26.6
60
26.6
N.A.
33.3
20
N.A.
33.3
60
26.6
6.6
N.A.
13.3
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
9
9
17
0
17
9
0
9
0
9
0
25
% A
% Cys:
0
0
0
0
0
17
0
9
0
0
0
0
0
17
0
% C
% Asp:
0
0
9
17
0
0
17
0
17
0
9
0
0
0
0
% D
% Glu:
0
9
25
9
9
0
0
9
0
0
17
25
9
9
0
% E
% Phe:
0
0
0
0
9
0
0
0
0
0
0
9
0
0
9
% F
% Gly:
9
0
0
0
17
0
0
0
9
0
0
0
0
17
0
% G
% His:
0
9
0
0
0
0
9
9
0
0
0
17
9
0
0
% H
% Ile:
9
0
9
9
9
0
0
9
9
17
0
0
0
0
9
% I
% Lys:
17
0
9
0
0
9
17
0
0
0
0
9
0
0
9
% K
% Leu:
0
17
0
0
17
9
9
9
9
17
9
9
0
34
0
% L
% Met:
9
0
0
0
0
0
17
0
0
9
0
0
0
0
0
% M
% Asn:
17
17
9
0
0
0
0
9
9
0
0
9
34
0
0
% N
% Pro:
0
0
9
9
0
34
0
0
0
25
0
0
17
17
17
% P
% Gln:
0
0
25
0
0
0
9
0
0
9
17
0
0
0
0
% Q
% Arg:
0
17
0
17
0
0
17
9
0
0
17
0
9
0
0
% R
% Ser:
17
34
9
17
0
0
0
9
9
0
17
9
0
0
9
% S
% Thr:
9
0
0
17
17
0
0
9
17
25
0
0
0
0
9
% T
% Val:
0
0
0
0
0
17
9
9
17
0
9
17
17
9
17
% V
% Trp:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _