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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BCL11B All Species: 21.52
Human Site: S258 Identified Species: 47.33
UniProt: Q9C0K0 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9C0K0 NP_075049.1 894 95519 S258 E P G P A S S S L T P R L T I
Chimpanzee Pan troglodytes XP_001151763 1027 110170 S391 E P G P A S S S L T P R L T I
Rhesus Macaque Macaca mulatta XP_001103061 894 95505 S258 E P G P A S S S L T P R L T I
Dog Lupus familis XP_538502 782 84726 H231 Q P P L H G I H I A D N N P F
Cat Felis silvestris
Mouse Mus musculus Q99PV8 884 94547 S258 E P G P A S T S L T P R L T I
Rat Rattus norvegicus NP_001101527 766 82070 P224 M G L V A Q H P S A F D R V M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512616 887 97215 S262 E T S P S N S S L T P R I T I
Chicken Gallus gallus XP_421354 882 96479 S257 E T S P S N S S L T P R I T I
Frog Xenopus laevis NP_001083346 727 79510 C187 P S G L G A E C P S Q P P L H
Zebra Danio Brachydanio rerio XP_002667906 654 72408 P114 P F V S P P P P R H P L E R L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781824 934 105063 F243 F P K D E R P F S R S R S V S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.3 99.7 54.3 N.A. 93.2 81.7 N.A. 82.4 81.5 50.7 49.1 N.A. N.A. N.A. N.A. 28.8
Protein Similarity: 100 86.8 99.7 64.2 N.A. 94.7 82.8 N.A. 88.3 87 61 56 N.A. N.A. N.A. N.A. 41.5
P-Site Identity: 100 100 100 6.6 N.A. 93.3 6.6 N.A. 66.6 66.6 6.6 6.6 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 100 20 N.A. 100 13.3 N.A. 86.6 86.6 20 13.3 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 46 10 0 0 0 19 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 0 0 0 0 0 10 10 0 0 0 % D
% Glu: 55 0 0 0 10 0 10 0 0 0 0 0 10 0 0 % E
% Phe: 10 10 0 0 0 0 0 10 0 0 10 0 0 0 10 % F
% Gly: 0 10 46 0 10 10 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 10 0 10 10 0 10 0 0 0 0 10 % H
% Ile: 0 0 0 0 0 0 10 0 10 0 0 0 19 0 55 % I
% Lys: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 10 19 0 0 0 0 55 0 0 10 37 10 10 % L
% Met: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 0 0 19 0 0 0 0 0 10 10 0 0 % N
% Pro: 19 55 10 55 10 10 19 19 10 0 64 10 10 10 0 % P
% Gln: 10 0 0 0 0 10 0 0 0 0 10 0 0 0 0 % Q
% Arg: 0 0 0 0 0 10 0 0 10 10 0 64 10 10 0 % R
% Ser: 0 10 19 10 19 37 46 55 19 10 10 0 10 0 10 % S
% Thr: 0 19 0 0 0 0 10 0 0 55 0 0 0 55 0 % T
% Val: 0 0 10 10 0 0 0 0 0 0 0 0 0 19 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _