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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC39A8
All Species:
15.76
Human Site:
T428
Identified Species:
38.52
UniProt:
Q9C0K1
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9C0K1
NP_001128618.1
460
49631
T428
E
K
V
T
G
R
K
T
D
F
T
F
F
M
I
Chimpanzee
Pan troglodytes
XP_001168271
452
48707
R420
P
E
M
N
D
M
L
R
E
K
V
T
G
R
K
Rhesus Macaque
Macaca mulatta
XP_001106660
743
81436
S711
Q
E
D
E
R
K
G
S
I
L
I
P
F
V
I
Dog
Lupus familis
XP_535673
636
67883
T604
E
K
I
T
G
R
K
T
D
F
T
Y
F
M
I
Cat
Felis silvestris
Mouse
Mus musculus
Q91W10
462
50063
T430
E
K
V
T
G
R
Q
T
D
F
T
F
F
M
I
Rat
Rattus norvegicus
Q5FVQ0
462
50153
T430
E
K
V
T
G
R
Q
T
D
F
T
F
F
M
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZI20
366
39255
P335
I
A
L
V
N
V
V
P
D
L
L
E
E
K
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6PEH9
847
95085
C812
D
S
E
E
H
K
R
C
E
M
G
H
F
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VSL7
706
77357
K661
P
E
I
S
A
S
H
K
S
L
G
Q
F
L
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XUC4
393
43305
N362
L
E
S
G
D
H
N
N
L
S
K
V
A
K
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
34.5
66
N.A.
88.9
87.6
N.A.
N.A.
22.6
N.A.
23.8
N.A.
22.7
N.A.
20.6
N.A.
Protein Similarity:
100
98.2
46.4
68.4
N.A.
93.2
92.2
N.A.
N.A.
35.6
N.A.
34
N.A.
35.4
N.A.
37.8
N.A.
P-Site Identity:
100
0
13.3
86.6
N.A.
93.3
93.3
N.A.
N.A.
6.6
N.A.
6.6
N.A.
6.6
N.A.
0
N.A.
P-Site Similarity:
100
20
46.6
100
N.A.
100
100
N.A.
N.A.
13.3
N.A.
46.6
N.A.
40
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
10
0
0
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
10
0
10
0
20
0
0
0
50
0
0
0
0
0
0
% D
% Glu:
40
40
10
20
0
0
0
0
20
0
0
10
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
40
0
30
70
0
0
% F
% Gly:
0
0
0
10
40
0
10
0
0
0
20
0
10
0
0
% G
% His:
0
0
0
0
10
10
10
0
0
0
0
10
0
0
0
% H
% Ile:
10
0
20
0
0
0
0
0
10
0
10
0
0
0
50
% I
% Lys:
0
40
0
0
0
20
20
10
0
10
10
0
0
20
10
% K
% Leu:
10
0
10
0
0
0
10
0
10
30
10
0
0
10
20
% L
% Met:
0
0
10
0
0
10
0
0
0
10
0
0
0
40
10
% M
% Asn:
0
0
0
10
10
0
10
10
0
0
0
0
0
0
10
% N
% Pro:
20
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% P
% Gln:
10
0
0
0
0
0
20
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
0
0
10
40
10
10
0
0
0
0
0
10
0
% R
% Ser:
0
10
10
10
0
10
0
10
10
10
0
0
0
0
0
% S
% Thr:
0
0
0
40
0
0
0
40
0
0
40
10
0
0
0
% T
% Val:
0
0
30
10
0
10
10
0
0
0
10
10
0
20
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _