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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR12
All Species:
20.3
Human Site:
S118
Identified Species:
31.9
UniProt:
Q9GZL7
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9GZL7
NP_060726.3
423
47708
S118
E
E
W
I
L
T
G
S
Y
D
K
T
S
R
I
Chimpanzee
Pan troglodytes
XP_516040
343
38363
E49
T
S
R
I
W
S
L
E
G
K
S
I
M
T
I
Rhesus Macaque
Macaca mulatta
XP_001105358
423
47651
S118
E
E
W
I
L
T
G
S
Y
D
K
T
S
R
I
Dog
Lupus familis
XP_536036
343
38158
E49
T
S
R
I
W
S
L
E
G
K
S
I
M
T
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJA4
423
47328
S118
E
E
W
I
L
S
G
S
Y
D
K
T
S
R
I
Rat
Rattus norvegicus
P61480
423
47544
S118
E
E
W
I
L
S
G
S
Y
D
K
T
S
R
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508954
423
47301
C118
E
E
W
I
L
T
G
C
Y
D
K
T
A
R
I
Chicken
Gallus gallus
XP_421945
418
46623
C113
E
E
W
I
L
T
G
C
Y
D
Q
T
A
R
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NX08
422
47263
S118
S
E
W
I
L
T
G
S
Y
D
K
T
A
R
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKQ3
420
47203
C123
G
K
W
I
L
S
G
C
Y
D
N
T
L
N
L
Honey Bee
Apis mellifera
XP_396848
424
48255
P107
E
K
Y
P
P
P
E
P
Q
D
C
L
I
H
D
Nematode Worm
Caenorhab. elegans
P91343
439
48984
T136
N
G
H
I
F
S
T
T
Y
G
G
D
I
V
I
Sea Urchin
Strong. purpuratus
XP_796128
443
48802
C129
G
E
R
I
L
T
G
C
Y
D
N
G
V
R
L
Poplar Tree
Populus trichocarpa
XP_002324109
433
47647
G127
C
P
R
F
I
L
T
G
C
Y
D
N
L
G
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12024
460
51340
S120
D
G
S
K
H
I
I
S
G
S
Y
D
G
I
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.1
98.8
74
N.A.
93.8
93.3
N.A.
88.8
82.2
N.A.
77.7
N.A.
41.6
48.1
30
51
Protein Similarity:
100
79.1
99.7
78.2
N.A.
97.8
97.8
N.A.
93.8
90
N.A.
90.5
N.A.
62.1
66.5
50.1
67.2
P-Site Identity:
100
13.3
100
13.3
N.A.
93.3
93.3
N.A.
86.6
80
N.A.
86.6
N.A.
46.6
13.3
20
53.3
P-Site Similarity:
100
20
100
20
N.A.
100
100
N.A.
93.3
93.3
N.A.
93.3
N.A.
66.6
26.6
33.3
60
Percent
Protein Identity:
35.5
N.A.
N.A.
N.A.
29.5
N.A.
Protein Similarity:
53.8
N.A.
N.A.
N.A.
46
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
20
0
0
% A
% Cys:
7
0
0
0
0
0
0
27
7
0
7
0
0
0
0
% C
% Asp:
7
0
0
0
0
0
0
0
0
67
7
14
0
0
7
% D
% Glu:
47
54
0
0
0
0
7
14
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
7
7
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
14
14
0
0
0
0
60
7
20
7
7
7
7
7
0
% G
% His:
0
0
7
0
7
0
0
0
0
0
0
0
0
7
0
% H
% Ile:
0
0
0
80
7
7
7
0
0
0
0
14
14
7
67
% I
% Lys:
0
14
0
7
0
0
0
0
0
14
40
0
0
0
0
% K
% Leu:
0
0
0
0
60
7
14
0
0
0
0
7
14
0
14
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
14
0
0
% M
% Asn:
7
0
0
0
0
0
0
0
0
0
14
7
0
7
0
% N
% Pro:
0
7
0
7
7
7
0
7
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
7
0
7
0
0
0
0
% Q
% Arg:
0
0
27
0
0
0
0
0
0
0
0
0
0
54
7
% R
% Ser:
7
14
7
0
0
40
0
40
0
7
14
0
27
0
0
% S
% Thr:
14
0
0
0
0
40
14
7
0
0
0
54
0
14
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
7
7
7
% V
% Trp:
0
0
54
0
14
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
0
0
67
7
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _