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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR12
All Species:
31.52
Human Site:
S127
Identified Species:
49.52
UniProt:
Q9GZL7
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9GZL7
NP_060726.3
423
47708
S127
D
K
T
S
R
I
W
S
L
E
G
K
S
I
M
Chimpanzee
Pan troglodytes
XP_516040
343
38363
G58
K
S
I
M
T
I
V
G
H
T
D
V
V
K
D
Rhesus Macaque
Macaca mulatta
XP_001105358
423
47651
S127
D
K
T
S
R
I
W
S
L
E
G
K
S
I
M
Dog
Lupus familis
XP_536036
343
38158
G58
K
S
I
M
T
I
V
G
H
T
D
V
V
K
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJA4
423
47328
S127
D
K
T
S
R
I
W
S
L
E
G
K
S
I
M
Rat
Rattus norvegicus
P61480
423
47544
S127
D
K
T
S
R
I
W
S
L
E
G
K
S
I
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508954
423
47301
S127
D
K
T
A
R
I
W
S
L
E
G
K
S
I
M
Chicken
Gallus gallus
XP_421945
418
46623
S122
D
Q
T
A
R
I
W
S
L
E
G
K
S
I
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NX08
422
47263
S127
D
K
T
A
R
I
W
S
M
E
G
K
A
V
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKQ3
420
47203
T132
D
N
T
L
N
L
W
T
N
K
G
K
H
I
L
Honey Bee
Apis mellifera
XP_396848
424
48255
W116
D
C
L
I
H
D
D
W
V
S
A
I
A
V
C
Nematode Worm
Caenorhab. elegans
P91343
439
48984
D145
G
G
D
I
V
I
V
D
R
K
G
K
E
T
K
Sea Urchin
Strong. purpuratus
XP_796128
443
48802
G138
D
N
G
V
R
L
W
G
R
N
G
D
N
I
A
Poplar Tree
Populus trichocarpa
XP_002324109
433
47647
W136
Y
D
N
L
G
R
V
W
K
A
A
G
E
C
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12024
460
51340
T129
S
Y
D
G
I
V
R
T
W
D
L
S
G
N
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.1
98.8
74
N.A.
93.8
93.3
N.A.
88.8
82.2
N.A.
77.7
N.A.
41.6
48.1
30
51
Protein Similarity:
100
79.1
99.7
78.2
N.A.
97.8
97.8
N.A.
93.8
90
N.A.
90.5
N.A.
62.1
66.5
50.1
67.2
P-Site Identity:
100
6.6
100
6.6
N.A.
100
100
N.A.
93.3
86.6
N.A.
73.3
N.A.
40
6.6
20
33.3
P-Site Similarity:
100
6.6
100
6.6
N.A.
100
100
N.A.
100
100
N.A.
100
N.A.
66.6
26.6
26.6
46.6
Percent
Protein Identity:
35.5
N.A.
N.A.
N.A.
29.5
N.A.
Protein Similarity:
53.8
N.A.
N.A.
N.A.
46
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
0
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
20
0
0
0
0
0
7
14
0
14
0
7
% A
% Cys:
0
7
0
0
0
0
0
0
0
0
0
0
0
7
7
% C
% Asp:
67
7
14
0
0
7
7
7
0
7
14
7
0
0
14
% D
% Glu:
0
0
0
0
0
0
0
0
0
47
0
0
14
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
7
7
7
7
0
0
20
0
0
67
7
7
0
0
% G
% His:
0
0
0
0
7
0
0
0
14
0
0
0
7
0
0
% H
% Ile:
0
0
14
14
7
67
0
0
0
0
0
7
0
54
0
% I
% Lys:
14
40
0
0
0
0
0
0
7
14
0
60
0
14
7
% K
% Leu:
0
0
7
14
0
14
0
0
40
0
7
0
0
0
7
% L
% Met:
0
0
0
14
0
0
0
0
7
0
0
0
0
0
47
% M
% Asn:
0
14
7
0
7
0
0
0
7
7
0
0
7
7
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
54
7
7
0
14
0
0
0
0
0
0
% R
% Ser:
7
14
0
27
0
0
0
47
0
7
0
7
40
0
0
% S
% Thr:
0
0
54
0
14
0
0
14
0
14
0
0
0
7
7
% T
% Val:
0
0
0
7
7
7
27
0
7
0
0
14
14
14
7
% V
% Trp:
0
0
0
0
0
0
60
14
7
0
0
0
0
0
0
% W
% Tyr:
7
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _