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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDR12 All Species: 20.91
Human Site: S200 Identified Species: 32.86
UniProt: Q9GZL7 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZL7 NP_060726.3 423 47708 S200 D S I A V D G S G T K F C S G
Chimpanzee Pan troglodytes XP_516040 343 38363 G121 S I A V D G S G T K F C S G S
Rhesus Macaque Macaca mulatta XP_001105358 423 47651 S200 D S V A V D G S G T K F C S G
Dog Lupus familis XP_536036 343 38158 G121 S I A V D S T G T K F C S G S
Cat Felis silvestris
Mouse Mus musculus Q9JJA4 423 47328 S200 D A I A V D S S G A K F C S G
Rat Rattus norvegicus P61480 423 47544 S200 D A I A V D S S G T K F C S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508954 423 47301 T200 D S I A V D S T G S K F C S G
Chicken Gallus gallus XP_421945 418 46623 T195 D S V A V D C T R T K F C S G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6NX08 422 47263 P199 V D T I A V D P T R T K F C S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VKQ3 420 47203 R195 S V C K G H E R G V D S V S V
Honey Bee Apis mellifera XP_396848 424 48255 I195 M E N S V D C I H V C R G H E
Nematode Worm Caenorhab. elegans P91343 439 48984 E215 R G H E R A V E C V S V N S D
Sea Urchin Strong. purpuratus XP_796128 443 48802 Q212 A V A V D Q S Q T R I C S G S
Poplar Tree Populus trichocarpa XP_002324109 433 47647 A206 K I L R G H N A P V Q S V A A
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12024 460 51340 G232 A S Y D N S I G F W S T I Y K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 76.1 98.8 74 N.A. 93.8 93.3 N.A. 88.8 82.2 N.A. 77.7 N.A. 41.6 48.1 30 51
Protein Similarity: 100 79.1 99.7 78.2 N.A. 97.8 97.8 N.A. 93.8 90 N.A. 90.5 N.A. 62.1 66.5 50.1 67.2
P-Site Identity: 100 0 93.3 0 N.A. 80 86.6 N.A. 80 73.3 N.A. 0 N.A. 13.3 13.3 6.6 0
P-Site Similarity: 100 0 100 0 N.A. 86.6 93.3 N.A. 93.3 86.6 N.A. 0 N.A. 13.3 20 6.6 0
Percent
Protein Identity: 35.5 N.A. N.A. N.A. 29.5 N.A.
Protein Similarity: 53.8 N.A. N.A. N.A. 46 N.A.
P-Site Identity: 0 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 26.6 N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 14 20 40 7 7 0 7 0 7 0 0 0 7 7 % A
% Cys: 0 0 7 0 0 0 14 0 7 0 7 20 40 7 0 % C
% Asp: 40 7 0 7 20 47 7 0 0 0 7 0 0 0 7 % D
% Glu: 0 7 0 7 0 0 7 7 0 0 0 0 0 0 7 % E
% Phe: 0 0 0 0 0 0 0 0 7 0 14 40 7 0 0 % F
% Gly: 0 7 0 0 14 7 14 20 40 0 0 0 7 20 40 % G
% His: 0 0 7 0 0 14 0 0 7 0 0 0 0 7 0 % H
% Ile: 0 20 27 7 0 0 7 7 0 0 7 0 7 0 0 % I
% Lys: 7 0 0 7 0 0 0 0 0 14 40 7 0 0 7 % K
% Leu: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 7 0 7 0 7 0 0 0 0 0 7 0 0 % N
% Pro: 0 0 0 0 0 0 0 7 7 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 7 0 7 0 0 7 0 0 0 0 % Q
% Arg: 7 0 0 7 7 0 0 7 7 14 0 7 0 0 0 % R
% Ser: 20 34 0 7 0 14 34 27 0 7 14 14 20 54 27 % S
% Thr: 0 0 7 0 0 0 7 14 27 27 7 7 0 0 0 % T
% Val: 7 14 14 20 47 7 7 0 0 27 0 7 14 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % W
% Tyr: 0 0 7 0 0 0 0 0 0 0 0 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _