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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDR12 All Species: 23.64
Human Site: S206 Identified Species: 37.14
UniProt: Q9GZL7 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZL7 NP_060726.3 423 47708 S206 G S G T K F C S G S W D K M L
Chimpanzee Pan troglodytes XP_516040 343 38363 G127 S G T K F C S G S W D K M L K
Rhesus Macaque Macaca mulatta XP_001105358 423 47651 S206 G S G T K F C S G S W D K M L
Dog Lupus familis XP_536036 343 38158 G127 T G T K F C S G S W D K M L K
Cat Felis silvestris
Mouse Mus musculus Q9JJA4 423 47328 S206 S S G A K F C S G S W D K M L
Rat Rattus norvegicus P61480 423 47544 S206 S S G T K F C S G S W D K M L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508954 423 47301 S206 S T G S K F C S G S W D K M L
Chicken Gallus gallus XP_421945 418 46623 S201 C T R T K F C S G S W D K M L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6NX08 422 47263 C205 D P T R T K F C S G S W D K M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VKQ3 420 47203 S201 E R G V D S V S V S P D G L R
Honey Bee Apis mellifera XP_396848 424 48255 H201 C I H V C R G H E R G L E A V
Nematode Worm Caenorhab. elegans P91343 439 48984 S221 V E C V S V N S D S T R A I S
Sea Urchin Strong. purpuratus XP_796128 443 48802 G218 S Q T R I C S G S F D K M L K
Poplar Tree Populus trichocarpa XP_002324109 433 47647 A212 N A P V Q S V A A E A S G S M
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12024 460 51340 Y238 I G F W S T I Y K E M T V V D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 76.1 98.8 74 N.A. 93.8 93.3 N.A. 88.8 82.2 N.A. 77.7 N.A. 41.6 48.1 30 51
Protein Similarity: 100 79.1 99.7 78.2 N.A. 97.8 97.8 N.A. 93.8 90 N.A. 90.5 N.A. 62.1 66.5 50.1 67.2
P-Site Identity: 100 0 100 0 N.A. 86.6 93.3 N.A. 80 80 N.A. 0 N.A. 26.6 0 13.3 0
P-Site Similarity: 100 6.6 100 6.6 N.A. 86.6 93.3 N.A. 93.3 86.6 N.A. 6.6 N.A. 33.3 13.3 20 6.6
Percent
Protein Identity: 35.5 N.A. N.A. N.A. 29.5 N.A.
Protein Similarity: 53.8 N.A. N.A. N.A. 46 N.A.
P-Site Identity: 0 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 26.6 N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 7 0 0 0 7 7 0 7 0 7 7 0 % A
% Cys: 14 0 7 0 7 20 40 7 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 7 0 0 0 7 0 20 47 7 0 7 % D
% Glu: 7 7 0 0 0 0 0 0 7 14 0 0 7 0 0 % E
% Phe: 0 0 7 0 14 40 7 0 0 7 0 0 0 0 0 % F
% Gly: 14 20 40 0 0 0 7 20 40 7 7 0 14 0 0 % G
% His: 0 0 7 0 0 0 0 7 0 0 0 0 0 0 0 % H
% Ile: 7 7 0 0 7 0 7 0 0 0 0 0 0 7 0 % I
% Lys: 0 0 0 14 40 7 0 0 7 0 0 20 40 7 20 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 7 0 27 40 % L
% Met: 0 0 0 0 0 0 0 0 0 0 7 0 20 40 14 % M
% Asn: 7 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % N
% Pro: 0 7 7 0 0 0 0 0 0 0 7 0 0 0 0 % P
% Gln: 0 7 0 0 7 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 7 7 14 0 7 0 0 0 7 0 7 0 0 7 % R
% Ser: 34 27 0 7 14 14 20 54 27 54 7 7 0 7 7 % S
% Thr: 7 14 27 27 7 7 0 0 0 0 7 7 0 0 0 % T
% Val: 7 0 0 27 0 7 14 0 7 0 0 0 7 7 7 % V
% Trp: 0 0 0 7 0 0 0 0 0 14 40 7 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _