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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDR12 All Species: 28.18
Human Site: S23 Identified Species: 44.29
UniProt: Q9GZL7 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZL7 NP_060726.3 423 47708 S23 A V D D V P F S I P A A S E I
Chimpanzee Pan troglodytes XP_516040 343 38363
Rhesus Macaque Macaca mulatta XP_001105358 423 47651 S23 A V D D V P F S I P A A S E I
Dog Lupus familis XP_536036 343 38158
Cat Felis silvestris
Mouse Mus musculus Q9JJA4 423 47328 S23 A V D D V P F S I P A A A E V
Rat Rattus norvegicus P61480 423 47544 S23 A V D D V P F S I P A T S E V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508954 423 47301 S23 T V D D V P F S V P A T S E I
Chicken Gallus gallus XP_421945 418 46623 A38 L I N K L L A A R G A D H K Y
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6NX08 422 47263 S23 L V D D V P F S I P A S S E V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VKQ3 420 47203 A29 A V P D V P Y A I D G T V T T
Honey Bee Apis mellifera XP_396848 424 48255 S36 A V P D F P L S V H T S I V S
Nematode Worm Caenorhab. elegans P91343 439 48984 D41 Q I P D A V F D V P T G A E C
Sea Urchin Strong. purpuratus XP_796128 443 48802 S32 V V G N T P F S V P A N V G V
Poplar Tree Populus trichocarpa XP_002324109 433 47647 A32 K V P N T S I A I P A N L T R
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12024 460 51340 Y29 H V Q D T P M Y A P I S L K R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 76.1 98.8 74 N.A. 93.8 93.3 N.A. 88.8 82.2 N.A. 77.7 N.A. 41.6 48.1 30 51
Protein Similarity: 100 79.1 99.7 78.2 N.A. 97.8 97.8 N.A. 93.8 90 N.A. 90.5 N.A. 62.1 66.5 50.1 67.2
P-Site Identity: 100 0 100 0 N.A. 86.6 86.6 N.A. 80 6.6 N.A. 80 N.A. 40 33.3 26.6 40
P-Site Similarity: 100 0 100 0 N.A. 100 93.3 N.A. 86.6 40 N.A. 93.3 N.A. 53.3 46.6 46.6 60
Percent
Protein Identity: 35.5 N.A. N.A. N.A. 29.5 N.A.
Protein Similarity: 53.8 N.A. N.A. N.A. 46 N.A.
P-Site Identity: 26.6 N.A. N.A. N.A. 26.6 N.A.
P-Site Similarity: 40 N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 40 0 0 0 7 0 7 20 7 0 60 20 14 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % C
% Asp: 0 0 40 67 0 0 0 7 0 7 0 7 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 47 0 % E
% Phe: 0 0 0 0 7 0 54 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 7 0 0 0 0 0 0 7 7 7 0 7 0 % G
% His: 7 0 0 0 0 0 0 0 0 7 0 0 7 0 0 % H
% Ile: 0 14 0 0 0 0 7 0 47 0 7 0 7 0 20 % I
% Lys: 7 0 0 7 0 0 0 0 0 0 0 0 0 14 0 % K
% Leu: 14 0 0 0 7 7 7 0 0 0 0 0 14 0 0 % L
% Met: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 7 14 0 0 0 0 0 0 0 14 0 0 0 % N
% Pro: 0 0 27 0 0 67 0 0 0 67 0 0 0 0 0 % P
% Gln: 7 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 14 % R
% Ser: 0 0 0 0 0 7 0 54 0 0 0 20 34 0 7 % S
% Thr: 7 0 0 0 20 0 0 0 0 0 14 20 0 14 7 % T
% Val: 7 74 0 0 47 7 0 0 27 0 0 0 14 7 27 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 7 7 0 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _