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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR12
All Species:
9.39
Human Site:
S230
Identified Species:
14.76
UniProt:
Q9GZL7
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9GZL7
NP_060726.3
423
47708
S230
E
E
D
E
M
E
E
S
T
N
R
P
R
K
K
Chimpanzee
Pan troglodytes
XP_516040
343
38363
T151
E
D
E
M
E
E
S
T
N
R
P
R
K
K
Q
Rhesus Macaque
Macaca mulatta
XP_001105358
423
47651
S230
E
E
D
E
M
E
E
S
T
N
R
P
R
K
K
Dog
Lupus familis
XP_536036
343
38158
T151
E
D
E
L
E
E
P
T
N
R
P
R
K
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJA4
423
47328
A230
E
E
D
E
M
E
E
A
T
N
R
P
R
K
K
Rat
Rattus norvegicus
P61480
423
47544
P230
E
E
D
E
I
Q
E
P
T
N
R
P
R
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508954
423
47301
G230
E
E
D
E
M
E
E
G
T
N
R
P
R
K
K
Chicken
Gallus gallus
XP_421945
418
46623
A225
E
E
D
E
M
E
E
A
A
N
R
P
R
K
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NX08
422
47263
E229
E
E
E
D
E
I
E
E
P
N
R
P
R
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKQ3
420
47203
L225
L
K
V
W
S
A
E
L
D
D
A
V
E
G
S
Honey Bee
Apis mellifera
XP_396848
424
48255
M225
A
T
G
A
W
D
T
M
L
K
I
W
S
T
D
Nematode Worm
Caenorhab. elegans
P91343
439
48984
E245
W
N
L
D
A
S
D
E
A
T
T
Y
E
K
E
Sea Urchin
Strong. purpuratus
XP_796128
443
48802
Q242
E
E
E
P
P
E
I
Q
E
Q
Q
K
K
R
V
Poplar Tree
Populus trichocarpa
XP_002324109
433
47647
E236
I
N
L
W
R
T
N
E
S
D
T
E
S
D
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12024
460
51340
R262
N
K
I
S
T
A
A
R
K
R
R
K
L
T
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.1
98.8
74
N.A.
93.8
93.3
N.A.
88.8
82.2
N.A.
77.7
N.A.
41.6
48.1
30
51
Protein Similarity:
100
79.1
99.7
78.2
N.A.
97.8
97.8
N.A.
93.8
90
N.A.
90.5
N.A.
62.1
66.5
50.1
67.2
P-Site Identity:
100
20
100
20
N.A.
93.3
80
N.A.
93.3
86.6
N.A.
60
N.A.
6.6
0
6.6
20
P-Site Similarity:
100
53.3
100
53.3
N.A.
100
93.3
N.A.
93.3
93.3
N.A.
73.3
N.A.
20
6.6
26.6
46.6
Percent
Protein Identity:
35.5
N.A.
N.A.
N.A.
29.5
N.A.
Protein Similarity:
53.8
N.A.
N.A.
N.A.
46
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
7
14
7
14
14
0
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
14
40
14
0
7
7
0
7
14
0
0
0
7
7
% D
% Glu:
67
54
27
40
20
54
54
20
7
0
0
7
14
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
7
0
0
0
0
7
0
0
0
0
0
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
7
0
7
7
7
0
0
0
7
0
0
0
0
% I
% Lys:
0
14
0
0
0
0
0
0
7
7
0
14
20
67
47
% K
% Leu:
7
0
14
7
0
0
0
7
7
0
0
0
7
0
7
% L
% Met:
0
0
0
7
34
0
0
7
0
0
0
0
0
0
7
% M
% Asn:
7
14
0
0
0
0
7
0
14
47
0
0
0
0
0
% N
% Pro:
0
0
0
7
7
0
7
7
7
0
14
47
0
0
0
% P
% Gln:
0
0
0
0
0
7
0
7
0
7
7
0
0
0
14
% Q
% Arg:
0
0
0
0
7
0
0
7
0
20
54
14
47
7
0
% R
% Ser:
0
0
0
7
7
7
7
14
7
0
0
0
14
0
7
% S
% Thr:
0
7
0
0
7
7
7
14
34
7
14
0
0
14
0
% T
% Val:
0
0
7
0
0
0
0
0
0
0
0
7
0
0
7
% V
% Trp:
7
0
0
14
7
0
0
0
0
0
0
7
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _