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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDR12 All Species: 39.09
Human Site: S316 Identified Species: 61.43
UniProt: Q9GZL7 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZL7 NP_060726.3 423 47708 S316 C K R L A S G S T D R H I R L
Chimpanzee Pan troglodytes XP_516040 343 38363 T237 K R L A S G S T D R H I R L W
Rhesus Macaque Macaca mulatta XP_001105358 423 47651 S316 C K R L A S G S T D R H I R L
Dog Lupus familis XP_536036 343 38158 T237 K R L A S G S T D R H I R L W
Cat Felis silvestris
Mouse Mus musculus Q9JJA4 423 47328 S316 C K R L A S G S T D R H I R L
Rat Rattus norvegicus P61480 423 47544 S316 C K R L A S G S T D R H I R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508954 423 47301 S316 C K R L A S G S T D R H I R L
Chicken Gallus gallus XP_421945 418 46623 S311 C R R L A S G S T D R H I R L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6NX08 422 47263 S315 C R R L A S G S T D R H V R L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VKQ3 420 47203 S311 N R L I L T A S A D K N L R L
Honey Bee Apis mellifera XP_396848 424 48255 S311 S F F D L D Y S P L S H T I I
Nematode Worm Caenorhab. elegans P91343 439 48984 P331 F T S I D L H P K S D L L I S
Sea Urchin Strong. purpuratus XP_796128 443 48802 S328 N G L L A S G S V D R H V R L
Poplar Tree Populus trichocarpa XP_002324109 433 47647 G322 L H C L H V G G E G S A L I A
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12024 460 51340 S348 L N L L A C G S S A R H I T L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 76.1 98.8 74 N.A. 93.8 93.3 N.A. 88.8 82.2 N.A. 77.7 N.A. 41.6 48.1 30 51
Protein Similarity: 100 79.1 99.7 78.2 N.A. 97.8 97.8 N.A. 93.8 90 N.A. 90.5 N.A. 62.1 66.5 50.1 67.2
P-Site Identity: 100 0 100 0 N.A. 100 100 N.A. 100 93.3 N.A. 86.6 N.A. 26.6 13.3 0 66.6
P-Site Similarity: 100 20 100 20 N.A. 100 100 N.A. 100 100 N.A. 100 N.A. 66.6 20 13.3 73.3
Percent
Protein Identity: 35.5 N.A. N.A. N.A. 29.5 N.A.
Protein Similarity: 53.8 N.A. N.A. N.A. 46 N.A.
P-Site Identity: 13.3 N.A. N.A. N.A. 53.3 N.A.
P-Site Similarity: 20 N.A. N.A. N.A. 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 14 60 0 7 0 7 7 0 7 0 0 7 % A
% Cys: 47 0 7 0 0 7 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 7 7 7 0 0 14 60 7 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % E
% Phe: 7 7 7 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 7 0 0 0 14 67 7 0 7 0 0 0 0 0 % G
% His: 0 7 0 0 7 0 7 0 0 0 14 67 0 0 0 % H
% Ile: 0 0 0 14 0 0 0 0 0 0 0 14 47 20 7 % I
% Lys: 14 34 0 0 0 0 0 0 7 0 7 0 0 0 0 % K
% Leu: 14 0 34 67 14 7 0 0 0 7 0 7 20 14 67 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 14 7 0 0 0 0 0 0 0 0 0 7 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 7 7 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 34 47 0 0 0 0 0 0 14 60 0 14 60 0 % R
% Ser: 7 0 7 0 14 54 14 74 7 7 14 0 0 0 7 % S
% Thr: 0 7 0 0 0 7 0 14 47 0 0 0 7 7 0 % T
% Val: 0 0 0 0 0 7 0 0 7 0 0 0 14 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14 % W
% Tyr: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _