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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR12
All Species:
31.52
Human Site:
S337
Identified Species:
49.52
UniProt:
Q9GZL7
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9GZL7
NP_060726.3
423
47708
S337
D
G
S
L
V
S
L
S
L
T
S
H
T
G
W
Chimpanzee
Pan troglodytes
XP_516040
343
38363
L258
G
S
L
V
S
L
S
L
T
S
H
T
G
W
V
Rhesus Macaque
Macaca mulatta
XP_001105358
423
47651
S337
D
G
S
L
V
S
L
S
L
T
S
H
T
G
W
Dog
Lupus familis
XP_536036
343
38158
L258
G
S
L
V
S
L
S
L
T
S
H
T
G
W
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJA4
423
47328
S337
D
G
S
L
V
S
L
S
L
T
S
H
T
G
W
Rat
Rattus norvegicus
P61480
423
47544
S337
D
G
S
L
V
S
L
S
L
T
S
H
T
G
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508954
423
47301
S337
D
G
S
L
V
L
L
S
L
T
S
H
T
G
W
Chicken
Gallus gallus
XP_421945
418
46623
S332
D
G
S
L
V
L
L
S
L
T
S
H
T
G
W
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NX08
422
47263
S336
D
G
S
L
V
L
L
S
L
T
S
H
N
G
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKQ3
420
47203
T332
Q
G
S
V
V
R
N
T
Y
L
G
H
N
A
W
Honey Bee
Apis mellifera
XP_396848
424
48255
R332
H
I
R
L
Y
D
P
R
S
T
E
G
S
L
V
Nematode Worm
Caenorhab. elegans
P91343
439
48984
N352
P
R
L
Y
D
P
K
N
R
D
G
S
M
V
K
Sea Urchin
Strong. purpuratus
XP_796128
443
48802
S349
D
G
A
V
V
K
S
S
L
T
H
H
N
G
W
Poplar Tree
Populus trichocarpa
XP_002324109
433
47647
R343
I
L
R
V
W
D
P
R
K
P
G
T
S
A
P
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12024
460
51340
Q369
A
S
S
K
V
T
Q
Q
Q
L
I
G
H
K
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.1
98.8
74
N.A.
93.8
93.3
N.A.
88.8
82.2
N.A.
77.7
N.A.
41.6
48.1
30
51
Protein Similarity:
100
79.1
99.7
78.2
N.A.
97.8
97.8
N.A.
93.8
90
N.A.
90.5
N.A.
62.1
66.5
50.1
67.2
P-Site Identity:
100
0
100
0
N.A.
100
100
N.A.
93.3
93.3
N.A.
86.6
N.A.
33.3
13.3
0
60
P-Site Similarity:
100
13.3
100
13.3
N.A.
100
100
N.A.
93.3
93.3
N.A.
86.6
N.A.
46.6
20
6.6
73.3
Percent
Protein Identity:
35.5
N.A.
N.A.
N.A.
29.5
N.A.
Protein Similarity:
53.8
N.A.
N.A.
N.A.
46
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
0
0
0
0
0
0
0
0
0
0
14
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
54
0
0
0
7
14
0
0
0
7
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
14
60
0
0
0
0
0
0
0
0
20
14
14
54
0
% G
% His:
7
0
0
0
0
0
0
0
0
0
20
60
7
0
0
% H
% Ile:
7
7
0
0
0
0
0
0
0
0
7
0
0
0
0
% I
% Lys:
0
0
0
7
0
7
7
0
7
0
0
0
0
7
7
% K
% Leu:
0
7
20
54
0
34
47
14
54
14
0
0
0
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
0
0
0
0
7
7
0
0
0
0
20
0
7
% N
% Pro:
7
0
0
0
0
7
14
0
0
7
0
0
0
0
7
% P
% Gln:
7
0
0
0
0
0
7
7
7
0
0
0
0
0
0
% Q
% Arg:
0
7
14
0
0
7
0
14
7
0
0
0
0
0
0
% R
% Ser:
0
20
60
0
14
27
20
54
7
14
47
7
14
0
0
% S
% Thr:
0
0
0
0
0
7
0
7
14
60
0
20
40
0
0
% T
% Val:
0
0
0
34
67
0
0
0
0
0
0
0
0
7
20
% V
% Trp:
0
0
0
0
7
0
0
0
0
0
0
0
0
14
60
% W
% Tyr:
0
0
0
7
7
0
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _