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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDR12 All Species: 34.85
Human Site: S374 Identified Species: 54.76
UniProt: Q9GZL7 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZL7 NP_060726.3 423 47708 S374 V K L W D T R S C K A P L Y D
Chimpanzee Pan troglodytes XP_516040 343 38363 C295 K L W D T R S C K A P L Y D L
Rhesus Macaque Macaca mulatta XP_001105358 423 47651 S374 V K L W D T R S C K A P L Y D
Dog Lupus familis XP_536036 343 38158 C295 K L W D T R S C K A P L Y D L
Cat Felis silvestris
Mouse Mus musculus Q9JJA4 423 47328 S374 V K L W D T R S C K A P L Y D
Rat Rattus norvegicus P61480 423 47544 S374 V K L W D T R S C K A P L Y D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508954 423 47301 S374 V K L W D T R S C K A P L Y D
Chicken Gallus gallus XP_421945 418 46623 S369 V K L W D T R S C K A P L Y D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6NX08 422 47263 S373 V K L W D T R S C K A P L Y D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VKQ3 420 47203 S369 N K L W D C R S P K A P L Y D
Honey Bee Apis mellifera XP_396848 424 48255 D369 L F I S G A Y D N D M K L W D
Nematode Worm Caenorhab. elegans P91343 439 48984 D389 Q F V S V S T D K T A K M W D
Sea Urchin Strong. purpuratus XP_796128 443 48802 S386 L K L W D I R S P K A P L F N
Poplar Tree Populus trichocarpa XP_002324109 433 47647 D380 H L L S A S Y D G K L M L W D
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12024 460 51340 R406 T V K V W D V R S T S P M Y T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 76.1 98.8 74 N.A. 93.8 93.3 N.A. 88.8 82.2 N.A. 77.7 N.A. 41.6 48.1 30 51
Protein Similarity: 100 79.1 99.7 78.2 N.A. 97.8 97.8 N.A. 93.8 90 N.A. 90.5 N.A. 62.1 66.5 50.1 67.2
P-Site Identity: 100 0 100 0 N.A. 100 100 N.A. 100 100 N.A. 100 N.A. 80 13.3 13.3 66.6
P-Site Similarity: 100 0 100 0 N.A. 100 100 N.A. 100 100 N.A. 100 N.A. 80 33.3 40 86.6
Percent
Protein Identity: 35.5 N.A. N.A. N.A. 29.5 N.A.
Protein Similarity: 53.8 N.A. N.A. N.A. 46 N.A.
P-Site Identity: 26.6 N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: 40 N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 7 7 0 0 0 14 67 0 0 0 0 % A
% Cys: 0 0 0 0 0 7 0 14 47 0 0 0 0 0 0 % C
% Asp: 0 0 0 14 60 7 0 20 0 7 0 0 0 14 74 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 14 0 0 0 0 0 0 0 0 0 0 0 7 0 % F
% Gly: 0 0 0 0 7 0 0 0 7 0 0 0 0 0 0 % G
% His: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 7 0 0 7 0 0 0 0 0 0 0 0 0 % I
% Lys: 14 60 7 0 0 0 0 0 20 67 0 14 0 0 0 % K
% Leu: 14 20 67 0 0 0 0 0 0 0 7 14 74 0 14 % L
% Met: 0 0 0 0 0 0 0 0 0 0 7 7 14 0 0 % M
% Asn: 7 0 0 0 0 0 0 0 7 0 0 0 0 0 7 % N
% Pro: 0 0 0 0 0 0 0 0 14 0 14 67 0 0 0 % P
% Gln: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 14 60 7 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 20 0 14 14 60 7 0 7 0 0 0 0 % S
% Thr: 7 0 0 0 14 47 7 0 0 14 0 0 0 0 7 % T
% Val: 47 7 7 7 7 0 7 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 14 60 7 0 0 0 0 0 0 0 0 20 0 % W
% Tyr: 0 0 0 0 0 0 14 0 0 0 0 0 14 60 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _