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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDR12 All Species: 20.91
Human Site: S391 Identified Species: 32.86
UniProt: Q9GZL7 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZL7 NP_060726.3 423 47708 S391 A H E D K V L S V D W T D T G
Chimpanzee Pan troglodytes XP_516040 343 38363 V312 H E D K V L S V D W T D T G L
Rhesus Macaque Macaca mulatta XP_001105358 423 47651 S391 A H E D K V L S V D W T D T G
Dog Lupus familis XP_536036 343 38158 V312 H E D K V L S V D W T D T G L
Cat Felis silvestris
Mouse Mus musculus Q9JJA4 423 47328 S391 A H E D K V L S V D W T D T G
Rat Rattus norvegicus P61480 423 47544 S391 A H E D K V L S V D W T D T G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508954 423 47301 S391 A H E D K V F S V D W T E T G
Chicken Gallus gallus XP_421945 418 46623 C386 A H E D K V L C V D W T E A G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6NX08 422 47263 C390 A H E D K V L C A D W T E N G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VKQ3 420 47203 D386 G H G E K V L D I D W S N P K
Honey Bee Apis mellifera XP_396848 424 48255 D386 S P K A P L F D L S G H E D K
Nematode Worm Caenorhab. elegans P91343 439 48984 D406 S S K S S L F D I H G H D D R
Sea Urchin Strong. purpuratus XP_796128 443 48802 T403 G L D D K I L T V D W S I P D
Poplar Tree Populus trichocarpa XP_002324109 433 47647 I397 T A W P L A I I D S H E D K V
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12024 460 51340 K423 R E D K S V Q K G V N D K V F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 76.1 98.8 74 N.A. 93.8 93.3 N.A. 88.8 82.2 N.A. 77.7 N.A. 41.6 48.1 30 51
Protein Similarity: 100 79.1 99.7 78.2 N.A. 97.8 97.8 N.A. 93.8 90 N.A. 90.5 N.A. 62.1 66.5 50.1 67.2
P-Site Identity: 100 0 100 0 N.A. 100 100 N.A. 86.6 80 N.A. 73.3 N.A. 40 0 6.6 40
P-Site Similarity: 100 13.3 100 13.3 N.A. 100 100 N.A. 93.3 86.6 N.A. 80 N.A. 66.6 33.3 33.3 66.6
Percent
Protein Identity: 35.5 N.A. N.A. N.A. 29.5 N.A.
Protein Similarity: 53.8 N.A. N.A. N.A. 46 N.A.
P-Site Identity: 6.6 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 13.3 N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 47 7 0 7 0 7 0 0 7 0 0 0 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 14 0 0 0 0 0 0 0 % C
% Asp: 0 0 27 54 0 0 0 20 20 60 0 20 40 14 7 % D
% Glu: 0 20 47 7 0 0 0 0 0 0 0 7 27 0 0 % E
% Phe: 0 0 0 0 0 0 20 0 0 0 0 0 0 0 7 % F
% Gly: 14 0 7 0 0 0 0 0 7 0 14 0 0 14 47 % G
% His: 14 54 0 0 0 0 0 0 0 7 7 14 0 0 0 % H
% Ile: 0 0 0 0 0 7 7 7 14 0 0 0 7 0 0 % I
% Lys: 0 0 14 20 60 0 0 7 0 0 0 0 7 7 14 % K
% Leu: 0 7 0 0 7 27 54 0 7 0 0 0 0 0 14 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 7 0 7 7 0 % N
% Pro: 0 7 0 7 7 0 0 0 0 0 0 0 0 14 0 % P
% Gln: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % Q
% Arg: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % R
% Ser: 14 7 0 7 14 0 14 34 0 14 0 14 0 0 0 % S
% Thr: 7 0 0 0 0 0 0 7 0 0 14 47 14 34 0 % T
% Val: 0 0 0 0 14 60 0 14 47 7 0 0 0 7 7 % V
% Trp: 0 0 7 0 0 0 0 0 0 14 60 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _