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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDR12 All Species: 38.79
Human Site: S77 Identified Species: 60.95
UniProt: Q9GZL7 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZL7 NP_060726.3 423 47708 S77 M E M E N I S S E E V V E I E
Chimpanzee Pan troglodytes XP_516040 343 38363 S8 M S S T N M W S L I S L L R A
Rhesus Macaque Macaca mulatta XP_001105358 423 47651 S77 V E L E N I S S E E V V E I E
Dog Lupus familis XP_536036 343 38158 S8 M S S T N M W S S I S L S R A
Cat Felis silvestris
Mouse Mus musculus Q9JJA4 423 47328 S77 M E L E N I S S E E V V E L E
Rat Rattus norvegicus P61480 423 47544 S77 M E L E D I S S E E V V E L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508954 423 47301 T77 M E L E N V S T E D V V E I E
Chicken Gallus gallus XP_421945 418 46623 T72 M E M E N I S T E E V V E I E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6NX08 422 47263 T77 I E T E N I S T E E V V E I E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VKQ3 420 47203 F82 L R E K A I S F E D A I E I E
Honey Bee Apis mellifera XP_396848 424 48255 F66 N I K N E I E F D F L V C S Q
Nematode Worm Caenorhab. elegans P91343 439 48984 T95 I E E Y E V E T E T I L K V E
Sea Urchin Strong. purpuratus XP_796128 443 48802 T88 F E V T Q T S T E A V V D I E
Poplar Tree Populus trichocarpa XP_002324109 433 47647 A86 L L A K G I S A E K V L E I E
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12024 460 51340 S79 L T K K G L S S E A S L N V E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 76.1 98.8 74 N.A. 93.8 93.3 N.A. 88.8 82.2 N.A. 77.7 N.A. 41.6 48.1 30 51
Protein Similarity: 100 79.1 99.7 78.2 N.A. 97.8 97.8 N.A. 93.8 90 N.A. 90.5 N.A. 62.1 66.5 50.1 67.2
P-Site Identity: 100 20 86.6 20 N.A. 86.6 80 N.A. 73.3 93.3 N.A. 80 N.A. 40 13.3 20 46.6
P-Site Similarity: 100 33.3 100 33.3 N.A. 100 100 N.A. 100 100 N.A. 93.3 N.A. 66.6 33.3 66.6 66.6
Percent
Protein Identity: 35.5 N.A. N.A. N.A. 29.5 N.A.
Protein Similarity: 53.8 N.A. N.A. N.A. 46 N.A.
P-Site Identity: 46.6 N.A. N.A. N.A. 26.6 N.A.
P-Site Similarity: 80 N.A. N.A. N.A. 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 7 0 0 7 0 14 7 0 0 0 14 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % C
% Asp: 0 0 0 0 7 0 0 0 7 14 0 0 7 0 0 % D
% Glu: 0 60 14 47 14 0 14 0 80 40 0 0 60 0 80 % E
% Phe: 7 0 0 0 0 0 0 14 0 7 0 0 0 0 0 % F
% Gly: 0 0 0 0 14 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 14 7 0 0 0 60 0 0 0 14 7 7 0 54 0 % I
% Lys: 0 0 14 20 0 0 0 0 0 7 0 0 7 0 0 % K
% Leu: 20 7 27 0 0 7 0 0 7 0 7 34 7 14 0 % L
% Met: 47 0 14 0 0 14 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 0 0 7 54 0 0 0 0 0 0 0 7 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 7 % Q
% Arg: 0 7 0 0 0 0 0 0 0 0 0 0 0 14 0 % R
% Ser: 0 14 14 0 0 0 74 47 7 0 20 0 7 7 0 % S
% Thr: 0 7 7 20 0 7 0 34 0 7 0 0 0 0 0 % T
% Val: 7 0 7 0 0 14 0 0 0 0 60 60 0 14 0 % V
% Trp: 0 0 0 0 0 0 14 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _