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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR12
All Species:
17.58
Human Site:
T218
Identified Species:
27.62
UniProt:
Q9GZL7
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9GZL7
NP_060726.3
423
47708
T218
K
M
L
K
I
W
S
T
V
P
T
D
E
E
D
Chimpanzee
Pan troglodytes
XP_516040
343
38363
V139
M
L
K
I
W
S
T
V
P
T
D
E
E
D
E
Rhesus Macaque
Macaca mulatta
XP_001105358
423
47651
T218
K
M
L
K
I
W
S
T
V
P
T
D
E
E
D
Dog
Lupus familis
XP_536036
343
38158
V139
M
L
K
I
W
S
A
V
P
T
D
E
E
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJA4
423
47328
T218
K
M
L
K
I
W
S
T
V
P
T
D
E
E
D
Rat
Rattus norvegicus
P61480
423
47544
T218
K
M
L
K
I
W
S
T
V
P
T
D
E
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508954
423
47301
A218
K
M
L
K
I
W
S
A
V
P
T
D
E
E
D
Chicken
Gallus gallus
XP_421945
418
46623
A213
K
M
L
K
I
W
S
A
V
P
T
D
E
E
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NX08
422
47263
S217
D
K
M
L
K
I
W
S
A
V
P
T
E
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKQ3
420
47203
S213
G
L
R
F
A
T
G
S
W
D
T
M
L
K
V
Honey Bee
Apis mellifera
XP_396848
424
48255
D213
E
A
V
N
I
N
Y
D
K
T
I
M
A
T
G
Nematode Worm
Caenorhab. elegans
P91343
439
48984
T233
A
I
S
G
S
V
D
T
N
L
K
I
W
N
L
Sea Urchin
Strong. purpuratus
XP_796128
443
48802
V230
M
L
K
V
W
S
A
V
P
S
S
G
E
E
E
Poplar Tree
Populus trichocarpa
XP_002324109
433
47647
S224
G
S
M
I
C
S
G
S
W
D
C
T
I
N
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12024
460
51340
I250
V
V
D
P
L
E
D
I
N
N
P
N
N
K
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.1
98.8
74
N.A.
93.8
93.3
N.A.
88.8
82.2
N.A.
77.7
N.A.
41.6
48.1
30
51
Protein Similarity:
100
79.1
99.7
78.2
N.A.
97.8
97.8
N.A.
93.8
90
N.A.
90.5
N.A.
62.1
66.5
50.1
67.2
P-Site Identity:
100
6.6
100
6.6
N.A.
100
100
N.A.
93.3
93.3
N.A.
13.3
N.A.
6.6
6.6
6.6
13.3
P-Site Similarity:
100
40
100
40
N.A.
100
100
N.A.
93.3
93.3
N.A.
33.3
N.A.
26.6
20
13.3
40
Percent
Protein Identity:
35.5
N.A.
N.A.
N.A.
29.5
N.A.
Protein Similarity:
53.8
N.A.
N.A.
N.A.
46
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
7
0
14
14
7
0
0
0
7
0
0
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
7
0
7
0
0
0
14
7
0
14
14
40
0
14
40
% D
% Glu:
7
0
0
0
0
7
0
0
0
0
0
14
67
54
27
% E
% Phe:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
14
0
0
7
0
0
14
0
0
0
0
7
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
20
47
7
0
7
0
0
7
7
7
0
7
% I
% Lys:
40
7
20
40
7
0
0
0
7
0
7
0
0
14
0
% K
% Leu:
0
27
40
7
7
0
0
0
0
7
0
0
7
0
14
% L
% Met:
20
40
14
0
0
0
0
0
0
0
0
14
0
0
0
% M
% Asn:
0
0
0
7
0
7
0
0
14
7
0
7
7
14
0
% N
% Pro:
0
0
0
7
0
0
0
0
20
40
14
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
7
7
0
7
27
40
20
0
7
7
0
0
0
0
% S
% Thr:
0
0
0
0
0
7
7
34
0
20
47
14
0
7
0
% T
% Val:
7
7
7
7
0
7
0
20
40
7
0
0
0
0
7
% V
% Trp:
0
0
0
0
20
40
7
0
14
0
0
0
7
0
0
% W
% Tyr:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _