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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WDR12
All Species:
18.04
Human Site:
T418
Identified Species:
28.35
UniProt:
Q9GZL7
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9GZL7
NP_060726.3
423
47708
T418
S
Y
R
Y
S
P
T
T
S
H
V
G
A
_
_
Chimpanzee
Pan troglodytes
XP_516040
343
38363
Rhesus Macaque
Macaca mulatta
XP_001105358
423
47651
T418
S
Y
R
Y
S
P
T
T
S
H
V
G
A
_
_
Dog
Lupus familis
XP_536036
343
38158
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJA4
423
47328
T418
S
Y
S
Y
S
P
T
T
S
H
V
G
A
_
_
Rat
Rattus norvegicus
P61480
423
47544
T418
S
Y
R
Y
S
P
T
T
S
H
V
G
A
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508954
423
47301
T418
S
Y
R
Y
S
A
T
T
S
D
V
G
A
_
_
Chicken
Gallus gallus
XP_421945
418
46623
A413
C
Y
R
Y
P
A
T
A
S
D
V
G
A
_
_
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NX08
422
47263
V417
T
Y
R
Y
A
A
C
V
S
D
A
G
A
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKQ3
420
47203
L413
V
F
K
S
R
K
A
L
A
E
E
A
E
T
K
Honey Bee
Apis mellifera
XP_396848
424
48255
T413
V
S
G
G
A
D
N
T
V
R
I
F
K
S
K
Nematode Worm
Caenorhab. elegans
P91343
439
48984
I433
T
G
S
A
D
C
T
I
K
I
F
E
T
A
_
Sea Urchin
Strong. purpuratus
XP_796128
443
48802
L430
M
F
S
T
A
E
A
L
S
T
T
E
S
S
T
Poplar Tree
Populus trichocarpa
XP_002324109
433
47647
L424
S
G
G
V
D
S
K
L
R
I
S
S
G
V
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12024
460
51340
Q450
A
G
Q
D
K
K
I
Q
I
N
K
G
D
N
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.1
98.8
74
N.A.
93.8
93.3
N.A.
88.8
82.2
N.A.
77.7
N.A.
41.6
48.1
30
51
Protein Similarity:
100
79.1
99.7
78.2
N.A.
97.8
97.8
N.A.
93.8
90
N.A.
90.5
N.A.
62.1
66.5
50.1
67.2
P-Site Identity:
100
0
100
0
N.A.
92.3
100
N.A.
84.6
61.5
N.A.
46.1
N.A.
0
6.6
7.1
6.6
P-Site Similarity:
100
0
100
0
N.A.
92.3
100
N.A.
84.6
61.5
N.A.
61.5
N.A.
20
20
14.2
26.6
Percent
Protein Identity:
35.5
N.A.
N.A.
N.A.
29.5
N.A.
Protein Similarity:
53.8
N.A.
N.A.
N.A.
46
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
20
20
14
7
7
0
7
7
47
7
0
% A
% Cys:
7
0
0
0
0
7
7
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
14
7
0
0
0
20
0
0
7
0
0
% D
% Glu:
0
0
0
0
0
7
0
0
0
7
7
14
7
0
0
% E
% Phe:
0
14
0
0
0
0
0
0
0
0
7
7
0
0
0
% F
% Gly:
0
20
14
7
0
0
0
0
0
0
0
54
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
27
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
7
7
7
14
7
0
0
0
7
% I
% Lys:
0
0
7
0
7
14
7
0
7
0
7
0
7
0
14
% K
% Leu:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
7
0
0
7
0
0
0
7
0
% N
% Pro:
0
0
0
0
7
27
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
7
0
0
0
0
7
0
0
0
0
0
0
0
% Q
% Arg:
0
0
40
0
7
0
0
0
7
7
0
0
0
0
0
% R
% Ser:
40
7
20
7
34
7
0
0
54
0
7
7
7
14
7
% S
% Thr:
14
0
0
7
0
0
47
40
0
7
7
0
7
7
7
% T
% Val:
14
0
0
7
0
0
0
7
7
0
40
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
47
0
47
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
47
54
% _