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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDR12 All Species: 23.64
Human Site: Y89 Identified Species: 37.14
UniProt: Q9GZL7 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZL7 NP_060726.3 423 47708 Y89 E I E Y V E K Y T A P Q P E Q
Chimpanzee Pan troglodytes XP_516040 343 38363 C20 L R A S F C E C P W T N T W K
Rhesus Macaque Macaca mulatta XP_001105358 423 47651 Y89 E I E Y V E K Y T A P Q P E Q
Dog Lupus familis XP_536036 343 38158 C20 S R A S F S G C P C S N T W N
Cat Felis silvestris
Mouse Mus musculus Q9JJA4 423 47328 Y89 E L E Y V E K Y T A P Q P E Q
Rat Rattus norvegicus P61480 423 47544 Y89 E L E Y V E K Y T A P Q P E Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508954 423 47301 Y89 E I E Y V E K Y T A P Q P E E
Chicken Gallus gallus XP_421945 418 46623 Y84 E I E Y V E K Y M A P Q P E E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6NX08 422 47263 F89 E I E Y V E K F T A P Q P E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VKQ3 420 47203 F94 E I E Y V E R F P A P E P Q D
Honey Bee Apis mellifera XP_396848 424 48255 S78 C S Q F L R T S L I E H I T E
Nematode Worm Caenorhab. elegans P91343 439 48984 I107 K V E C V I G I E A P K P L H
Sea Urchin Strong. purpuratus XP_796128 443 48802 Q100 D I E Y V V K Q T A P E P V G
Poplar Tree Populus trichocarpa XP_002324109 433 47647 V98 E I E Y T R A V V L Q K E D E
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12024 460 51340 I91 N V E Y T R A I L P P S Y L N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 76.1 98.8 74 N.A. 93.8 93.3 N.A. 88.8 82.2 N.A. 77.7 N.A. 41.6 48.1 30 51
Protein Similarity: 100 79.1 99.7 78.2 N.A. 97.8 97.8 N.A. 93.8 90 N.A. 90.5 N.A. 62.1 66.5 50.1 67.2
P-Site Identity: 100 0 100 0 N.A. 93.3 93.3 N.A. 93.3 86.6 N.A. 86.6 N.A. 60 0 33.3 60
P-Site Similarity: 100 13.3 100 0 N.A. 100 100 N.A. 100 93.3 N.A. 100 N.A. 86.6 26.6 53.3 73.3
Percent
Protein Identity: 35.5 N.A. N.A. N.A. 29.5 N.A.
Protein Similarity: 53.8 N.A. N.A. N.A. 46 N.A.
P-Site Identity: 26.6 N.A. N.A. N.A. 20 N.A.
P-Site Similarity: 46.6 N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 14 0 0 0 14 0 0 67 0 0 0 0 0 % A
% Cys: 7 0 0 7 0 7 0 14 0 7 0 0 0 0 0 % C
% Asp: 7 0 0 0 0 0 0 0 0 0 0 0 0 7 7 % D
% Glu: 60 0 80 0 0 54 7 0 7 0 7 14 7 47 34 % E
% Phe: 0 0 0 7 14 0 0 14 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 14 0 0 0 0 0 0 0 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 7 % H
% Ile: 0 54 0 0 0 7 0 14 0 7 0 0 7 0 0 % I
% Lys: 7 0 0 0 0 0 54 0 0 0 0 14 0 0 7 % K
% Leu: 7 14 0 0 7 0 0 0 14 7 0 0 0 14 0 % L
% Met: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % M
% Asn: 7 0 0 0 0 0 0 0 0 0 0 14 0 0 14 % N
% Pro: 0 0 0 0 0 0 0 0 20 7 74 0 67 0 0 % P
% Gln: 0 0 7 0 0 0 0 7 0 0 7 47 0 7 27 % Q
% Arg: 0 14 0 0 0 20 7 0 0 0 0 0 0 0 0 % R
% Ser: 7 7 0 14 0 7 0 7 0 0 7 7 0 0 0 % S
% Thr: 0 0 0 0 14 0 7 0 47 0 7 0 14 7 0 % T
% Val: 0 14 0 0 67 7 0 7 7 0 0 0 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 7 0 0 0 14 0 % W
% Tyr: 0 0 0 74 0 0 0 40 0 0 0 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _