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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GPR88 All Species: 15.15
Human Site: S349 Identified Species: 41.67
UniProt: Q9GZN0 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZN0 NP_071332.2 384 40246 S349 E F R R S V R S V L P G V G D
Chimpanzee Pan troglodytes Q5IS65 440 46934 R333 D F K R A L G R F L P C P R C
Rhesus Macaque Macaca mulatta P47899 480 51591 R392 D F R N A F Q R L L C C A R R
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9EPB7 384 40222 S349 E F R R S V R S V L P G V G D
Rat Rattus norvegicus Q9ESP4 384 40181 S349 E F R R S V R S V L P G V G D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514547 375 41400 L317 S Y I P F L L L N I I D M R G
Chicken Gallus gallus XP_001232659 428 46112 S315 E F R R A A R S V L P R A E G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001342529 345 38814 S305 E F R K S F R S V M R G D F L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120910 312 34980 A279 T N K L Y R E A Y K Q I L C P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 22.7 23.3 N.A. N.A. 95.5 95.3 N.A. 23.7 47.6 N.A. 35.9 N.A. N.A. 23.9 N.A. N.A.
Protein Similarity: 100 36.3 35.8 N.A. N.A. 96.8 96.3 N.A. 36.9 54.6 N.A. 51 N.A. N.A. 39.5 N.A. N.A.
P-Site Identity: 100 26.6 20 N.A. N.A. 100 100 N.A. 0 60 N.A. 53.3 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 100 53.3 46.6 N.A. N.A. 100 100 N.A. 26.6 66.6 N.A. 66.6 N.A. N.A. 20 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 34 12 0 12 0 0 0 0 23 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 12 23 0 12 12 % C
% Asp: 23 0 0 0 0 0 0 0 0 0 0 12 12 0 34 % D
% Glu: 56 0 0 0 0 0 12 0 0 0 0 0 0 12 0 % E
% Phe: 0 78 0 0 12 23 0 0 12 0 0 0 0 12 0 % F
% Gly: 0 0 0 0 0 0 12 0 0 0 0 45 0 34 23 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 12 0 0 0 0 0 0 12 12 12 0 0 0 % I
% Lys: 0 0 23 12 0 0 0 0 0 12 0 0 0 0 0 % K
% Leu: 0 0 0 12 0 23 12 12 12 67 0 0 12 0 12 % L
% Met: 0 0 0 0 0 0 0 0 0 12 0 0 12 0 0 % M
% Asn: 0 12 0 12 0 0 0 0 12 0 0 0 0 0 0 % N
% Pro: 0 0 0 12 0 0 0 0 0 0 56 0 12 0 12 % P
% Gln: 0 0 0 0 0 0 12 0 0 0 12 0 0 0 0 % Q
% Arg: 0 0 67 56 0 12 56 23 0 0 12 12 0 34 12 % R
% Ser: 12 0 0 0 45 0 0 56 0 0 0 0 0 0 0 % S
% Thr: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 34 0 0 56 0 0 0 34 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 12 0 0 12 0 0 0 12 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _