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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACTR6 All Species: 17.58
Human Site: S263 Identified Species: 27.62
UniProt: Q9GZN1 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZN1 NP_071941.1 396 45810 S263 V L S G K Y K S G E Q I L R L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001088805 288 33191 E165 Q I L R L A N E R F A V P E I
Dog Lupus familis XP_532663 201 23111 F80 L R L A N E R F A V P E I L F
Cat Felis silvestris
Mouse Mus musculus Q9D864 396 45767 S263 V L S G K Y K S G E Q I L R L
Rat Rattus norvegicus NP_001101551 396 45767 S263 V L S G K Y K S G E Q I L R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q9DEE9 396 45766 T263 V L S G K Y K T G E Q I L R L
Frog Xenopus laevis NP_001091370 396 45496 A263 V F S G K T T A G E Q I L R L
Zebra Danio Brachydanio rerio NP_955990 396 45733 T263 N F T G K Y K T G E Q I L R L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P45890 398 45396 Q271 R E D E E Q Q Q M V S L C N E
Honey Bee Apis mellifera XP_393258 391 45057 L265 N E Q Q T L R L S N E R F A I
Nematode Worm Caenorhab. elegans Q09443 418 47599 I263 H D P Q I P S I H L G V E R F
Sea Urchin Strong. purpuratus XP_001188386 394 45254 V266 Q K P N E Q I V R M N N E R F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8LGE3 421 46925 E272 F L S L S E K E S V V V M D K
Baker's Yeast Sacchar. cerevisiae Q12509 438 50025 L306 E D A Q I I T L T D E L F T I
Red Bread Mold Neurospora crassa Q7S6X6 446 49867 P295 G V V R D Y E P G V S A R A R
Conservation
Percent
Protein Identity: 100 N.A. 72.7 50.7 N.A. 98.7 98.7 N.A. N.A. 95.1 89.1 83.5 N.A. 45.9 58.8 36.3 63.8
Protein Similarity: 100 N.A. 72.7 50.7 N.A. 100 100 N.A. N.A. 98.9 95.9 92.6 N.A. 66.8 78.2 59.3 79.2
P-Site Identity: 100 N.A. 0 0 N.A. 100 100 N.A. N.A. 93.3 73.3 73.3 N.A. 0 0 6.6 6.6
P-Site Similarity: 100 N.A. 20 20 N.A. 100 100 N.A. N.A. 100 80 86.6 N.A. 20 20 13.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. 35.8 29.2 34.7
Protein Similarity: N.A. N.A. N.A. 57.7 48.1 52.9
P-Site Identity: N.A. N.A. N.A. 20 0 13.3
P-Site Similarity: N.A. N.A. N.A. 33.3 33.3 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 7 0 7 0 7 7 0 7 7 0 14 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % C
% Asp: 0 14 7 0 7 0 0 0 0 7 0 0 0 7 0 % D
% Glu: 7 14 0 7 14 14 7 14 0 40 14 7 14 7 7 % E
% Phe: 7 14 0 0 0 0 0 7 0 7 0 0 14 0 20 % F
% Gly: 7 0 0 40 0 0 0 0 47 0 7 0 0 0 0 % G
% His: 7 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % H
% Ile: 0 7 0 0 14 7 7 7 0 0 0 40 7 0 20 % I
% Lys: 0 7 0 0 40 0 40 0 0 0 0 0 0 0 7 % K
% Leu: 7 34 14 7 7 7 0 14 0 7 0 14 40 7 40 % L
% Met: 0 0 0 0 0 0 0 0 7 7 0 0 7 0 0 % M
% Asn: 14 0 0 7 7 0 7 0 0 7 7 7 0 7 0 % N
% Pro: 0 0 14 0 0 7 0 7 0 0 7 0 7 0 0 % P
% Gln: 14 0 7 20 0 14 7 7 0 0 40 0 0 0 0 % Q
% Arg: 7 7 0 14 0 0 14 0 14 0 0 7 7 54 7 % R
% Ser: 0 0 40 0 7 0 7 20 14 0 14 0 0 0 0 % S
% Thr: 0 0 7 0 7 7 14 14 7 0 0 0 0 7 0 % T
% Val: 34 7 7 0 0 0 0 7 0 27 7 20 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 40 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _