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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACTR6 All Species: 32.73
Human Site: S301 Identified Species: 51.43
UniProt: Q9GZN1 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZN1 NP_071941.1 396 45810 S301 I P E A I V Y S I Q N L P E E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001088805 288 33191 N196 A I V Y S I Q N L P E E M Q P
Dog Lupus familis XP_532663 201 23111 P111 V Y S I Q N L P E E M Q P H F
Cat Felis silvestris
Mouse Mus musculus Q9D864 396 45767 S301 I P E A I V Y S I Q N L P E E
Rat Rattus norvegicus NP_001101551 396 45767 S301 I P E A I V Y S I Q N L P E E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q9DEE9 396 45766 S301 I P E A I V D S I Q N L P E E
Frog Xenopus laevis NP_001091370 396 45496 S301 I P E A I V H S I N N L P E E
Zebra Danio Brachydanio rerio NP_955990 396 45733 S301 I P E A L V N S I N N M P E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P45890 398 45396 C306 I P E A V A D C L K A C P W E
Honey Bee Apis mellifera XP_393258 391 45057 C296 I P E A I M D C L K A C D E E
Nematode Worm Caenorhab. elegans Q09443 418 47599 S296 V A E A V I E S I C Q C P E A
Sea Urchin Strong. purpuratus XP_001188386 394 45254 S299 I S E A I V H S I S A T P K E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8LGE3 421 46925 A326 L A E C I V R A I N S C H S Y
Baker's Yeast Sacchar. cerevisiae Q12509 438 50025 S337 I V E A I L E S L S M L P E I
Red Bread Mold Neurospora crassa Q7S6X6 446 49867 S345 I A D L V K Q S L L A V P I G
Conservation
Percent
Protein Identity: 100 N.A. 72.7 50.7 N.A. 98.7 98.7 N.A. N.A. 95.1 89.1 83.5 N.A. 45.9 58.8 36.3 63.8
Protein Similarity: 100 N.A. 72.7 50.7 N.A. 100 100 N.A. N.A. 98.9 95.9 92.6 N.A. 66.8 78.2 59.3 79.2
P-Site Identity: 100 N.A. 0 6.6 N.A. 100 100 N.A. N.A. 93.3 86.6 73.3 N.A. 40 46.6 40 60
P-Site Similarity: 100 N.A. 26.6 20 N.A. 100 100 N.A. N.A. 93.3 93.3 86.6 N.A. 60 66.6 60 73.3
Percent
Protein Identity: N.A. N.A. N.A. 35.8 29.2 34.7
Protein Similarity: N.A. N.A. N.A. 57.7 48.1 52.9
P-Site Identity: N.A. N.A. N.A. 26.6 53.3 20
P-Site Similarity: N.A. N.A. N.A. 46.6 66.6 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 20 0 74 0 7 0 7 0 0 27 0 0 0 7 % A
% Cys: 0 0 0 7 0 0 0 14 0 7 0 27 0 0 0 % C
% Asp: 0 0 7 0 0 0 20 0 0 0 0 0 7 0 0 % D
% Glu: 0 0 80 0 0 0 14 0 7 7 7 7 0 60 60 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % G
% His: 0 0 0 0 0 0 14 0 0 0 0 0 7 7 0 % H
% Ile: 74 7 0 7 60 14 0 0 60 0 0 0 0 7 7 % I
% Lys: 0 0 0 0 0 7 0 0 0 14 0 0 0 7 0 % K
% Leu: 7 0 0 7 7 7 7 0 34 7 0 40 0 0 0 % L
% Met: 0 0 0 0 0 7 0 0 0 0 14 7 7 0 0 % M
% Asn: 0 0 0 0 0 7 7 7 0 20 40 0 0 0 0 % N
% Pro: 0 54 0 0 0 0 0 7 0 7 0 0 80 0 7 % P
% Gln: 0 0 0 0 7 0 14 0 0 27 7 7 0 7 0 % Q
% Arg: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % R
% Ser: 0 7 7 0 7 0 0 67 0 14 7 0 0 7 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % T
% Val: 14 7 7 0 20 54 0 0 0 0 0 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % W
% Tyr: 0 7 0 7 0 0 20 0 0 0 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _