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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACTR6 All Species: 26.36
Human Site: S348 Identified Species: 41.43
UniProt: Q9GZN1 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZN1 NP_071941.1 396 45810 S348 T P T D Y D V S V V L P E N P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001088805 288 33191 S240 T P T D Y D V S V V L P E N P
Dog Lupus familis XP_532663 201 23111 V154 P T D Y D V S V V L P E N P I
Cat Felis silvestris
Mouse Mus musculus Q9D864 396 45767 S348 T P T D Y D V S V V L P E N P
Rat Rattus norvegicus NP_001101551 396 45767 S348 T P T D Y D V S V V L P E N P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q9DEE9 396 45766 S348 T P T D Y D V S V V L P E N P
Frog Xenopus laevis NP_001091370 396 45496 S348 T P T D F D V S V I L P E N P
Zebra Danio Brachydanio rerio NP_955990 396 45733 S348 A P V E Y D V S V V L P N N P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P45890 398 45396 L350 R A L V P D D L E V S L I C P
Honey Bee Apis mellifera XP_393258 391 45057 N343 A P A E Y T I N V Y L P E N P
Nematode Worm Caenorhab. elegans Q09443 418 47599 N343 L P A E Y G L N V S N D V I N
Sea Urchin Strong. purpuratus XP_001188386 394 45254 Q346 A P V E Y D V Q V T L P P N P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8LGE3 421 46925 K373 V P D H F D V K I T T Q E D P
Baker's Yeast Sacchar. cerevisiae Q12509 438 50025 V385 P T D W T C H V S V P E G D C
Red Bread Mold Neurospora crassa Q7S6X6 446 49867 R392 F P D E C R V R V A R P E D P
Conservation
Percent
Protein Identity: 100 N.A. 72.7 50.7 N.A. 98.7 98.7 N.A. N.A. 95.1 89.1 83.5 N.A. 45.9 58.8 36.3 63.8
Protein Similarity: 100 N.A. 72.7 50.7 N.A. 100 100 N.A. N.A. 98.9 95.9 92.6 N.A. 66.8 78.2 59.3 79.2
P-Site Identity: 100 N.A. 100 6.6 N.A. 100 100 N.A. N.A. 100 86.6 73.3 N.A. 20 53.3 20 60
P-Site Similarity: 100 N.A. 100 13.3 N.A. 100 100 N.A. N.A. 100 100 80 N.A. 20 73.3 40 66.6
Percent
Protein Identity: N.A. N.A. N.A. 35.8 29.2 34.7
Protein Similarity: N.A. N.A. N.A. 57.7 48.1 52.9
P-Site Identity: N.A. N.A. N.A. 33.3 6.6 40
P-Site Similarity: N.A. N.A. N.A. 53.3 13.3 53.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 7 14 0 0 0 0 0 0 7 0 0 0 0 0 % A
% Cys: 0 0 0 0 7 7 0 0 0 0 0 0 0 7 7 % C
% Asp: 0 0 27 40 7 67 7 0 0 0 0 7 0 20 0 % D
% Glu: 0 0 0 34 0 0 0 0 7 0 0 14 60 0 0 % E
% Phe: 7 0 0 0 14 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 7 0 0 0 0 0 0 7 0 0 % G
% His: 0 0 0 7 0 0 7 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 7 0 7 7 0 0 7 7 7 % I
% Lys: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % K
% Leu: 7 0 7 0 0 0 7 7 0 7 60 7 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 14 0 0 7 0 14 60 7 % N
% Pro: 14 80 0 0 7 0 0 0 0 0 14 67 7 7 80 % P
% Gln: 0 0 0 0 0 0 0 7 0 0 0 7 0 0 0 % Q
% Arg: 7 0 0 0 0 7 0 7 0 0 7 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 7 47 7 7 7 0 0 0 0 % S
% Thr: 40 14 40 0 7 7 0 0 0 14 7 0 0 0 0 % T
% Val: 7 0 14 7 0 7 67 14 80 54 0 0 7 0 0 % V
% Trp: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 60 0 0 0 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _