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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACTR6 All Species: 18.79
Human Site: S388 Identified Species: 29.52
UniProt: Q9GZN1 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZN1 NP_071941.1 396 45810 S388 D Y E E N G H S V C E E K F D
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001088805 288 33191 S280 D Y E E N G H S V C E E K F D
Dog Lupus familis XP_532663 201 23111 V194 Y E E N G H S V C E E K F D I
Cat Felis silvestris
Mouse Mus musculus Q9D864 396 45767 S388 D Y E E N G H S V C E E K F D
Rat Rattus norvegicus NP_001101551 396 45767 S388 D Y E E N G H S V C E E K F D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q9DEE9 396 45766 N388 D Y E E H G H N I C E E K F D
Frog Xenopus laevis NP_001091370 396 45496 A388 D Y E E N G H A I C E E K F D
Zebra Danio Brachydanio rerio NP_955990 396 45733 Y388 D Y E E N G H Y I C E E K F D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P45890 398 45396 Y390 T Q D D Y E E Y G F Q G I N Q
Honey Bee Apis mellifera XP_393258 391 45057 N383 D Y E E E G Q N L C F E R F D
Nematode Worm Caenorhab. elegans Q09443 418 47599 L383 W D E R G D S L E F S N F F Q
Sea Urchin Strong. purpuratus XP_001188386 394 45254 N386 Q Y E E E G Q N I C F D K F D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8LGE3 421 46925 A413 E Y E E L G S A R C R R R F F
Baker's Yeast Sacchar. cerevisiae Q12509 438 50025 D425 E Y Y E H G P D W C T K H R F
Red Bread Mold Neurospora crassa Q7S6X6 446 49867 A432 E Y E E H G A A W V A R K F A
Conservation
Percent
Protein Identity: 100 N.A. 72.7 50.7 N.A. 98.7 98.7 N.A. N.A. 95.1 89.1 83.5 N.A. 45.9 58.8 36.3 63.8
Protein Similarity: 100 N.A. 72.7 50.7 N.A. 100 100 N.A. N.A. 98.9 95.9 92.6 N.A. 66.8 78.2 59.3 79.2
P-Site Identity: 100 N.A. 100 13.3 N.A. 100 100 N.A. N.A. 80 86.6 86.6 N.A. 0 60 13.3 53.3
P-Site Similarity: 100 N.A. 100 20 N.A. 100 100 N.A. N.A. 100 100 93.3 N.A. 20 80 13.3 73.3
Percent
Protein Identity: N.A. N.A. N.A. 35.8 29.2 34.7
Protein Similarity: N.A. N.A. N.A. 57.7 48.1 52.9
P-Site Identity: N.A. N.A. N.A. 40 26.6 40
P-Site Similarity: N.A. N.A. N.A. 60 46.6 60
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 7 20 0 0 7 0 0 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 7 74 0 0 0 0 0 % C
% Asp: 54 7 7 7 0 7 0 7 0 0 0 7 0 7 60 % D
% Glu: 20 7 87 80 14 7 7 0 7 7 54 54 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 14 14 0 14 80 14 % F
% Gly: 0 0 0 0 14 80 0 0 7 0 0 7 0 0 0 % G
% His: 0 0 0 0 20 7 47 0 0 0 0 0 7 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 27 0 0 0 7 0 7 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 14 60 0 0 % K
% Leu: 0 0 0 0 7 0 0 7 7 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 7 40 0 0 20 0 0 0 7 0 7 0 % N
% Pro: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % P
% Gln: 7 7 0 0 0 0 14 0 0 0 7 0 0 0 14 % Q
% Arg: 0 0 0 7 0 0 0 0 7 0 7 14 14 7 0 % R
% Ser: 0 0 0 0 0 0 20 27 0 0 7 0 0 0 0 % S
% Thr: 7 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 7 27 7 0 0 0 0 0 % V
% Trp: 7 0 0 0 0 0 0 0 14 0 0 0 0 0 0 % W
% Tyr: 7 80 7 0 7 0 0 14 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _