Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACTR6 All Species: 31.52
Human Site: T357 Identified Species: 49.52
UniProt: Q9GZN1 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZN1 NP_071941.1 396 45810 T357 V L P E N P I T Y A W E G G K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001088805 288 33191 T249 V L P E N P I T Y A W E G G K
Dog Lupus familis XP_532663 201 23111 Y163 L P E N P I T Y A W E G G K L
Cat Felis silvestris
Mouse Mus musculus Q9D864 396 45767 T357 V L P E N P I T Y S W E G G K
Rat Rattus norvegicus NP_001101551 396 45767 T357 V L P E N P I T Y S W E G G K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q9DEE9 396 45766 T357 V L P E N P I T Y S W E G G K
Frog Xenopus laevis NP_001091370 396 45496 S357 I L P E N P I S Y S W E G G K
Zebra Danio Brachydanio rerio NP_955990 396 45733 C357 V L P N N P I C Y S W E G G K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P45890 398 45396 D359 V S L I C P E D P V R Y A W Y
Honey Bee Apis mellifera XP_393258 391 45057 T352 Y L P E N P V T Y A W Q G G K
Nematode Worm Caenorhab. elegans Q09443 418 47599 Q352 S N D V I N P Q T H S W H C G
Sea Urchin Strong. purpuratus XP_001188386 394 45254 T355 T L P P N P V T Y A W E G G K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8LGE3 421 46925 L382 T T Q E D P I L G V W R G G S
Baker's Yeast Sacchar. cerevisiae Q12509 438 50025 L394 V P E G D C A L F G W E V M S
Red Bread Mold Neurospora crassa Q7S6X6 446 49867 I401 A R P E D P I I S T W L G A A
Conservation
Percent
Protein Identity: 100 N.A. 72.7 50.7 N.A. 98.7 98.7 N.A. N.A. 95.1 89.1 83.5 N.A. 45.9 58.8 36.3 63.8
Protein Similarity: 100 N.A. 72.7 50.7 N.A. 100 100 N.A. N.A. 98.9 95.9 92.6 N.A. 66.8 78.2 59.3 79.2
P-Site Identity: 100 N.A. 100 6.6 N.A. 93.3 93.3 N.A. N.A. 93.3 80 80 N.A. 13.3 80 0 80
P-Site Similarity: 100 N.A. 100 13.3 N.A. 100 100 N.A. N.A. 100 100 86.6 N.A. 13.3 93.3 0 86.6
Percent
Protein Identity: N.A. N.A. N.A. 35.8 29.2 34.7
Protein Similarity: N.A. N.A. N.A. 57.7 48.1 52.9
P-Site Identity: N.A. N.A. N.A. 40 20 40
P-Site Similarity: N.A. N.A. N.A. 46.6 33.3 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 0 0 0 7 0 7 27 0 0 7 7 7 % A
% Cys: 0 0 0 0 7 7 0 7 0 0 0 0 0 7 0 % C
% Asp: 0 0 7 0 20 0 0 7 0 0 0 0 0 0 0 % D
% Glu: 0 0 14 60 0 0 7 0 0 0 7 60 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % F
% Gly: 0 0 0 7 0 0 0 0 7 7 0 7 80 67 7 % G
% His: 0 0 0 0 0 0 0 0 0 7 0 0 7 0 0 % H
% Ile: 7 0 0 7 7 7 60 7 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 60 % K
% Leu: 7 60 7 0 0 0 0 14 0 0 0 7 0 0 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % M
% Asn: 0 7 0 14 60 7 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 14 67 7 7 80 7 0 7 0 0 0 0 0 0 % P
% Gln: 0 0 7 0 0 0 0 7 0 0 0 7 0 0 0 % Q
% Arg: 0 7 0 0 0 0 0 0 0 0 7 7 0 0 0 % R
% Ser: 7 7 0 0 0 0 0 7 7 34 7 0 0 0 14 % S
% Thr: 14 7 0 0 0 0 7 47 7 7 0 0 0 0 0 % T
% Val: 54 0 0 7 0 0 14 0 0 14 0 0 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 7 80 7 0 7 0 % W
% Tyr: 7 0 0 0 0 0 0 7 60 0 0 7 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _