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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACTR6 All Species: 25.45
Human Site: Y334 Identified Species: 40
UniProt: Q9GZN1 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.21
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZN1 NP_071941.1 396 45810 Y334 P G F R D R V Y S E V R C L T
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001088805 288 33191 Y226 P G F R D R V Y S E V R C L T
Dog Lupus familis XP_532663 201 23111 S140 G F R D R V Y S E V R C L T P
Cat Felis silvestris
Mouse Mus musculus Q9D864 396 45767 Y334 P G F R E R V Y S E V R C L T
Rat Rattus norvegicus NP_001101551 396 45767 Y334 P G F R E R V Y S E V R C L T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q9DEE9 396 45766 Y334 P G F R D R V Y S E V R C L T
Frog Xenopus laevis NP_001091370 396 45496 F334 P G F R E R V F S E V R K L T
Zebra Danio Brachydanio rerio NP_955990 396 45733 Y334 P G F R D R V Y K E V R A L A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P45890 398 45396 P336 A Q F P G F L P R L K R D L R
Honey Bee Apis mellifera XP_393258 391 45057 Y329 P G F Q E R I Y K E V R S L A
Nematode Worm Caenorhab. elegans Q09443 418 47599 E329 P G F R E R L E R E V R S M L
Sea Urchin Strong. purpuratus XP_001188386 394 45254 E332 P G V K E R V E K D V R S L A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8LGE3 421 46925 E359 P Q L K E R L E G E L R P L V
Baker's Yeast Sacchar. cerevisiae Q12509 438 50025 A371 N F A Q R L A A E L Q R Q L P
Red Bread Mold Neurospora crassa Q7S6X6 446 49867 Q378 E G F C Q R L Q T E I L K R F
Conservation
Percent
Protein Identity: 100 N.A. 72.7 50.7 N.A. 98.7 98.7 N.A. N.A. 95.1 89.1 83.5 N.A. 45.9 58.8 36.3 63.8
Protein Similarity: 100 N.A. 72.7 50.7 N.A. 100 100 N.A. N.A. 98.9 95.9 92.6 N.A. 66.8 78.2 59.3 79.2
P-Site Identity: 100 N.A. 100 0 N.A. 93.3 93.3 N.A. N.A. 100 80 80 N.A. 20 60 53.3 46.6
P-Site Similarity: 100 N.A. 100 0 N.A. 100 100 N.A. N.A. 100 93.3 80 N.A. 26.6 80 73.3 66.6
Percent
Protein Identity: N.A. N.A. N.A. 35.8 29.2 34.7
Protein Similarity: N.A. N.A. N.A. 57.7 48.1 52.9
P-Site Identity: N.A. N.A. N.A. 33.3 13.3 26.6
P-Site Similarity: N.A. N.A. N.A. 60 20 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 7 0 0 0 7 7 0 0 0 0 7 0 20 % A
% Cys: 0 0 0 7 0 0 0 0 0 0 0 7 34 0 0 % C
% Asp: 0 0 0 7 27 0 0 0 0 7 0 0 7 0 0 % D
% Glu: 7 0 0 0 47 0 0 20 14 74 0 0 0 0 0 % E
% Phe: 0 14 74 0 0 7 0 7 0 0 0 0 0 0 7 % F
% Gly: 7 74 0 0 7 0 0 0 7 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 7 0 0 0 7 0 0 0 0 % I
% Lys: 0 0 0 14 0 0 0 0 20 0 7 0 14 0 0 % K
% Leu: 0 0 7 0 0 7 27 0 0 14 7 7 7 80 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % M
% Asn: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 74 0 0 7 0 0 0 7 0 0 0 0 7 0 14 % P
% Gln: 0 14 0 14 7 0 0 7 0 0 7 0 7 0 0 % Q
% Arg: 0 0 7 54 14 80 0 0 14 0 7 87 0 7 7 % R
% Ser: 0 0 0 0 0 0 0 7 40 0 0 0 20 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 7 0 0 0 0 7 40 % T
% Val: 0 0 7 0 0 7 54 0 0 7 67 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 7 47 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _