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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACTR6 All Species: 43.33
Human Site: Y382 Identified Species: 68.1
UniProt: Q9GZN1 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZN1 NP_071941.1 396 45810 Y382 M V V T R E D Y E E N G H S V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001088805 288 33191 Y274 M V V T R E D Y E E N G H S V
Dog Lupus familis XP_532663 201 23111 E188 V V T R E D Y E E N G H S V C
Cat Felis silvestris
Mouse Mus musculus Q9D864 396 45767 Y382 M V V T R E D Y E E N G H S V
Rat Rattus norvegicus NP_001101551 396 45767 Y382 M V V T R E D Y E E N G H S V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q9DEE9 396 45766 Y382 L V V T R E D Y E E H G H N I
Frog Xenopus laevis NP_001091370 396 45496 Y382 M V V T R E D Y E E N G H A I
Zebra Danio Brachydanio rerio NP_955990 396 45733 Y382 M A V T R D D Y E E N G H Y I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P45890 398 45396 Q384 F E E F V Y T Q D D Y E E Y G
Honey Bee Apis mellifera XP_393258 391 45057 Y377 L L V T R E D Y E E E G Q N L
Nematode Worm Caenorhab. elegans Q09443 418 47599 D377 W I N R K D W D E R G D S L E
Sea Urchin Strong. purpuratus XP_001188386 394 45254 Y380 L T V S K K Q Y E E E G Q N I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8LGE3 421 46925 Y407 M C V T K A E Y E E L G S A R
Baker's Yeast Sacchar. cerevisiae Q12509 438 50025 Y419 A R V T R E E Y Y E H G P D W
Red Bread Mold Neurospora crassa Q7S6X6 446 49867 Y426 L E V T K Q E Y E E H G A A W
Conservation
Percent
Protein Identity: 100 N.A. 72.7 50.7 N.A. 98.7 98.7 N.A. N.A. 95.1 89.1 83.5 N.A. 45.9 58.8 36.3 63.8
Protein Similarity: 100 N.A. 72.7 50.7 N.A. 100 100 N.A. N.A. 98.9 95.9 92.6 N.A. 66.8 78.2 59.3 79.2
P-Site Identity: 100 N.A. 100 13.3 N.A. 100 100 N.A. N.A. 73.3 86.6 73.3 N.A. 0 60 6.6 33.3
P-Site Similarity: 100 N.A. 100 26.6 N.A. 100 100 N.A. N.A. 100 100 86.6 N.A. 13.3 86.6 26.6 73.3
Percent
Protein Identity: N.A. N.A. N.A. 35.8 29.2 34.7
Protein Similarity: N.A. N.A. N.A. 57.7 48.1 52.9
P-Site Identity: N.A. N.A. N.A. 46.6 46.6 40
P-Site Similarity: N.A. N.A. N.A. 66.6 60 80
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 0 0 0 7 0 0 0 0 0 0 7 20 0 % A
% Cys: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 7 % C
% Asp: 0 0 0 0 0 20 54 7 7 7 0 7 0 7 0 % D
% Glu: 0 14 7 0 7 54 20 7 87 80 14 7 7 0 7 % E
% Phe: 7 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 14 80 0 0 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 20 7 47 0 0 % H
% Ile: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 27 % I
% Lys: 0 0 0 0 27 7 0 0 0 0 0 0 0 0 0 % K
% Leu: 27 7 0 0 0 0 0 0 0 0 7 0 0 7 7 % L
% Met: 47 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 7 0 0 0 0 0 0 7 40 0 0 20 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % P
% Gln: 0 0 0 0 0 7 7 7 0 0 0 0 14 0 0 % Q
% Arg: 0 7 0 14 60 0 0 0 0 7 0 0 0 0 7 % R
% Ser: 0 0 0 7 0 0 0 0 0 0 0 0 20 27 0 % S
% Thr: 0 7 7 74 0 0 7 0 0 0 0 0 0 0 0 % T
% Val: 7 47 80 0 7 0 0 0 0 0 0 0 0 7 27 % V
% Trp: 7 0 0 0 0 0 7 0 0 0 0 0 0 0 14 % W
% Tyr: 0 0 0 0 0 7 7 80 7 0 7 0 0 14 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _