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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACTR6 All Species: 31.82
Human Site: Y77 Identified Species: 50
UniProt: Q9GZN1 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9GZN1 NP_071941.1 396 45810 Y77 V Q R Q V W D Y L F G K E M Y
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001088805 288 33191
Dog Lupus familis XP_532663 201 23111
Cat Felis silvestris
Mouse Mus musculus Q9D864 396 45767 Y77 V Q R Q V W D Y L F G K E M Y
Rat Rattus norvegicus NP_001101551 396 45767 Y77 V Q R Q V W D Y L F G K E M Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q9DEE9 396 45766 Y77 V Q R Q V W D Y L F G K E M Y
Frog Xenopus laevis NP_001091370 396 45496 Y77 V Q R Q V W D Y L F G K E M F
Zebra Danio Brachydanio rerio NP_955990 396 45733 H77 V Q R K V W D H L F G K E M F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P45890 398 45396 Y80 T Q K T V W D Y I F S K D G I
Honey Bee Apis mellifera XP_393258 391 45057 Y79 V Q K T V W D Y I F S K E C C
Nematode Worm Caenorhab. elegans Q09443 418 47599 K80 T Q Q Q I W E K T F G S M D V
Sea Urchin Strong. purpuratus XP_001188386 394 45254 Y80 V Q R Q V W D Y M F G K E L L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8LGE3 421 46925 S86 I W S H L F T S L L H I A P S
Baker's Yeast Sacchar. cerevisiae Q12509 438 50025 Y78 L E S C I W D Y C L F N P S E
Red Bread Mold Neurospora crassa Q7S6X6 446 49867 F100 K E I W D R E F F D D K A A Q
Conservation
Percent
Protein Identity: 100 N.A. 72.7 50.7 N.A. 98.7 98.7 N.A. N.A. 95.1 89.1 83.5 N.A. 45.9 58.8 36.3 63.8
Protein Similarity: 100 N.A. 72.7 50.7 N.A. 100 100 N.A. N.A. 98.9 95.9 92.6 N.A. 66.8 78.2 59.3 79.2
P-Site Identity: 100 N.A. 0 0 N.A. 100 100 N.A. N.A. 100 93.3 80 N.A. 46.6 60 33.3 80
P-Site Similarity: 100 N.A. 0 0 N.A. 100 100 N.A. N.A. 100 100 100 N.A. 66.6 73.3 53.3 93.3
Percent
Protein Identity: N.A. N.A. N.A. 35.8 29.2 34.7
Protein Similarity: N.A. N.A. N.A. 57.7 48.1 52.9
P-Site Identity: N.A. N.A. N.A. 6.6 20 6.6
P-Site Similarity: N.A. N.A. N.A. 26.6 40 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 14 7 0 % A
% Cys: 0 0 0 7 0 0 0 0 7 0 0 0 0 7 7 % C
% Asp: 0 0 0 0 7 0 67 0 0 7 7 0 7 7 0 % D
% Glu: 0 14 0 0 0 0 14 0 0 0 0 0 54 0 7 % E
% Phe: 0 0 0 0 0 7 0 7 7 67 7 0 0 0 14 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 54 0 0 7 0 % G
% His: 0 0 0 7 0 0 0 7 0 0 7 0 0 0 0 % H
% Ile: 7 0 7 0 14 0 0 0 14 0 0 7 0 0 7 % I
% Lys: 7 0 14 7 0 0 0 7 0 0 0 67 0 0 0 % K
% Leu: 7 0 0 0 7 0 0 0 47 14 0 0 0 7 7 % L
% Met: 0 0 0 0 0 0 0 0 7 0 0 0 7 40 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 7 7 0 % P
% Gln: 0 67 7 47 0 0 0 0 0 0 0 0 0 0 7 % Q
% Arg: 0 0 47 0 0 7 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 14 0 0 0 0 7 0 0 14 7 0 7 7 % S
% Thr: 14 0 0 14 0 0 7 0 7 0 0 0 0 0 0 % T
% Val: 54 0 0 0 60 0 0 0 0 0 0 0 0 0 7 % V
% Trp: 0 7 0 7 0 74 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 60 0 0 0 0 0 0 27 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _